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Olfactory protective effect of omega-3 supplements during healing after endoscopic sellar and parasellar resection

This multicentre study, led by researchers from Stanford, demonstrates another use for omega-3 supplements. The study analysed cohorts equally divided between control arm and omega-3 supplementation. Post endoscopic sellar and parasellar resection, better olfactory function was observed at three and...

To scan or not to scan?

This comprehensive review article seeks to establish how useful is MRI in the evaluation of patients with a history of smell loss or distortion. Interestingly, while some studies found the imaging unhelpful, one paper described found a 25% rate of...

Earlier intervention to correct anosmia?

This is an interesting study aimed to determine the timing for successful surgical intervention in improving the sense of smell in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). A total of 86 CRSwNP patients with loss of smell and...

CRSwNP and smell – is it just the obstruction?

Anosmia and hyposmia are symptoms of CRS both with and without nasal polyps and can significantly affect quality of life. The nature of anosmia/hyposmia is thought to be both sensory-neural and conductive. These authors studied a mouse model in which...

Long-term results for dupilumab are very promising!

Eosinophilic chronic rhinosinusitis (eCRS) is complicated by frequent early and aggressive recurrence of polyps after both medical and surgical treatment regimes. Dupilumab is an anti-IL-4/IL-3 receptor monoclonal antibody and has been previously studied in the SINUS-52 study, with an observation...

Nasal polyps, does size matter?

This study from Germany investigates the correlation between nasal polyp size and return of olfactory function following endoscopic sinus surgery. Olfaction is affected more in patients with CRSwNP than with CRSsNP and the best chance of smell recovery occurs in...

Does septoplasty improve smell?

This is a study from Barcelona on a very interesting topic: does septoplasty change sense of smell? The theory being that a deviated septum would prevent airflow to the olfactory region and once the anatomical obstruction has been relieved, that...

Smell training is also effective in older patients

Olfactory loss is a common problem with a significant impact on quality of life. It has been demonstrated that olfactory training (OT) improves olfactory function in younger patients, but this study focuses in on patients aged 45 years and older....

Management of smell and taste disorders – A practical guide for clinicians

This textbook with 240 pages is well laid out, very well illustrated including colour photographs and has excellent summary boxes at the end of individual sections. Up to one fifth of adults have some form of olfactory dysfunction and as...