You searched for "molecular"
Clinicopathological features of follicular variant of papillary thyroid carcinoma
The follicular variant (FV) of papillary thyroid carcinoma (PTC) is characterised by the presence of nuclear features of PTC together with a follicular growth pattern. It is currently reported to make up 11.8% to 53.3% of all PTC cases. It...What’s new in laryngology: the next 10 years!
At a time of unprecedented technological advances, Taran Tatla and Jonathan Fishman gaze into the laryngological crystal ball… Introduction The recent explosion in science, technology and innovation takes us into a new era, with the opportunity and capability to transform...Thyroid cancer – the last decade
Professor Ashok Shaha describes the evolution in the treatment of thyroid cancer that he has witnessed over the last decade and the invaluable progress made by himself and others, from their contributions to staging systems and guidelines. Nuances and paradigm...Getting to grips with acoustic trauma
Our understanding of hearing loss caused by noise exposure to those in the armed forces is growing in interest and understanding. Research at a cellular level is essential to increase our understanding so that we can better diagnose, manage and...The search for pharmacological treatments for hearing loss and tinnitus
Where are we in our search for a hearing restoration grail? Nicola Robas leads us through the map pieces discovered in creating a pharmaceutical answer to hearing loss and tinnitus. Together, hearing loss and tinnitus affect over one in six...
Salivary Gland Neoplasms
Salivary Gland Neoplasms is another useful addition to the Advances in Otolaryngology series. This issue (Vol 78) sees Prof Patrick Bradley (Nottingham) and David Eisele (Baltimore) co-edit a 206-page edition, nicely divided into 23 chapters, covering basics like molecular pathology,...
Hydrogen peroxide and its uses in healthcare
This is an interesting review about the origin and uses of hydrogen peroxide, especially in neurosurgery. However, its uses are ubiquitous and applicable to several medical specialties. When hydrogen peroxide was first discovered in 1818 by Louis Thenard, it had...
One airway, one disease - not for everyone!
While 85% of asthmatic patients have rhinitis, only 20-30% with rhinitis have asthma. Together with atopic dermatitis (AD), rhinitis and asthma form a triad that tend to co-exist in patients (multimorbidity). This co-existence raises the possibility of genetic mechanism. Authors...
Percutaneous tracheostomy in anticoagulated patients
This Belgian study looked at the risks and complications of bedside percutaneous tracheostomy in patients who received anticoagulant therapy. The 231 tracheostomies included in the study were performed over an eight-year period by two otolaryngologists using bronchoscopic guidance. The mean...
Chronic rhinosinusitis, are we treating the same disease?
Chronic rhinosinusitis (CRS) is a heterogenic disease. The effects of heterogeneity on treatment outcome are not very clear. Authors used clinical features such as endoscopic findings scores and full blood count findings in addition to analysis of 35 molecular markers....
Are cardiovascular risk factors associated with hearing loss?
Cardiovascular disease (CVD) risk factors are associated with microvascular damage that can impair molecular transport across capillary walls and cause inflammation and oxidative stress that may damage cochlear structure and function. This study determined, among a population-based sample of Canadian...
