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Review of surgical treatments of intractable Meniere’s disease

This is a nice summary of the evidence available for the surgical treatments for intractable Meniere’s disease. To summarise, in five-10 years, over 90% of vestibular neurectomy cases, more than 80% of intratympanic gentamycin treatment, and 70-80% of endolymphatic sac...

Thyroid dysfunction and Meniere’s disease: is there a relationship?

The set of symptoms described as Meniere’s disease may have several causative factors. Timothy Hain and Patthida Maroongroge look for a relationship in the literature between Meniere’s disease and hypothyroidism. Meniere’s disease (MD) affects around two in 1000 people and...

The evidence for various treatments of autoimmune ear disease

The difficulty with this disease entity is that it is a heterogeneous group of conditions affecting the ear and a widely accepted diagnostic criteria does not exist. It is therefore difficult to conduct a well controlled trial and this systematic...

Sing it, say it, sort it: singing for Parkinson’s disease

Parkinson’s disease (PD) occurs in 1% of the population aged over 60. Changes in voice and speech are among the earliest and most prevalent symptoms of PD; reduced vocal intensity, monopitch, monoloudness, breathy and hoarse voice quality, imprecise articulation, vocal...

Neurological idiopathic disease: a shared journey for NASA and medicine

Whilst Southampton can’t really be described as an extreme environment, experiments carried out in the city have certainly been taken out of this world. Robert Marchbanks discusses one of the associations between Southampton, The International Space Station and tympanic membrane...

Gadolinium enhanced MRI and the diagnosis of Ménière’s disease

Despite various criteria applied over the years to diagnose Ménière’s disease since the concept of endolymphatic hydrops was first observed in postmortem examinations of patients in 1938, the diagnosis still remains mainly clinical. To visualise endolymphatic hydrops in MRI imaging,...

Clinical features of BPPV in Meniere’s disease

It is an observation that BPPV appears to be commonly associated with Meniere’s disease (MD). This five-year study compared features and treatment outcomes between patients presenting with MD in conjunction with unilateral BPPV and a group of BPPV patients without...

Association between Meniere’s disease and vestibular migraine

Meniere’s disease (MD) and vestibular migraine (VM) are two conditions with overlap in their symptoms. There is often a lack of understanding regarding symptom-based differentiation between them. MD presents with episodic vertigo, fluctuating hearing loss and tinnitus. MD has been...

Discovery in the genetics of complex disease: Otitis media

Otitis media (OM), a common disease of childhood, is considered to be a complex trait with multiple genetic and environmental factors expected to contribute to a child’s risk of developing recurrent acute OM (rAOM; ≥3 episodes in 6 months or...

Endolymphatic sac surgery for Ménière’s disease

This is a very useful meta-analysis for those that perform surgery for Ménière’s disease. It specifically looked at differences in various forms of endolymphatic sac surgery (ESS). A total of 36 papers were included. The results: ESS controls vertigo in...

Chronic rhinosinusitis, are we treating the same disease?

Chronic rhinosinusitis (CRS) is a heterogenic disease. The effects of heterogeneity on treatment outcome are not very clear. Authors used clinical features such as endoscopic findings scores and full blood count findings in addition to analysis of 35 molecular markers....

Radiology and sinus disease: “the ever-evolving landscape”

Computed tomography (CT) remains the imaging modality of choice in assessment of patients with symptoms of chronic rhinosinusitis resistant to conservative treatment. In the last 10 years, CT technology has seen significant advances with the development and integration of multi-detector...