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The unknown primary again

In this retrospective study of 35 patients, the authors followed a systematic protocol for the detection and management of malignant cervical lymph nodes without an apparent primary lesion. Although their one, three and five year survival results are consistent with...

The sentinel lymph nodes revisited

The concept of sentinel lymph node sampling has been around for some time. However, its acceptability in routine head and neck practice has yet to be established. This article presents the authors’ experience in 10 patients with Merkel cell carcinoma...

Core biopsies are good enough for lymphomas

This paper, from the South of England, has reviewed ultrasound-guided core needle biopsies over a six-year period investigating the use of the detection of head and neck lymphomas. There were 367 samples included from 226 patients; 215 of the 226...

Choline PET-CT: an accurate diagnostic tool for the detection of parathyroid adenoma?

Hyperparathyroidism (HPT) is an endocrine disorder characterised by an increase in the secretion of parathyroid hormone (PTH), with a resulting increase in calcium plasma levels, which can cause renal lithiasis, fractures, and osteoporosis, the most frequent symptoms of the disease....

Can you hear the speech disorder?

Dysarthria is often the first or most pronounced feature of a Parkinson’s disease (PD) presentation, yet may be difficult to discern from normal ageing changes that impact voice and speech. Thus, it is important to be able to differentiate in...

Differences between paediatric and adult cholesteatomas

An understanding of the differences between adult and paediatric cholesteatomas should be helpful in more effective management of the disease in children. In this study, the authors focused their comparison between paediatric and adult cholesteatomas to the operative findings, rates...

Are upper respiratory symptoms and macroscopic changes in children always due to gastro-oesphageal reflux?

In children, symptoms such as chronic cough, wheezing, stridor, voice changes, persistent asthma and dental erosion are often presumed to be due to gastro-oesophageal reflux and empirical treatment with PPIs is offered. Usual investigations, such as a barium meal, gastroscopy...

Amount of dietary iodine and thyroid cancer

Two molecular scientists from Zurich wrote this paper as a systematic review, asking the question of whether dietary iodine intake is a risk factor for developing thyroid cancer later on life. They speculate that low iodine intake is a risk...

Facial Landmark localisation by curvature maps and profile analysis

The detection of three dimensional (3D) landmarks by scanning surfaces is a well established method in medical science. Anatomical landmarks are visually or palpably detectable and act as reference points for clinical measurements. When measuring these landmarks with a sliding...