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From the editor Jul/Aug 2024
Declan Costello, MA, MBBS, FRCS(ORL-HNS),Consultant Ear, Nose and Throat Surgeon, Wexham Park Hospital, Slough, Berkshire, UK. E: d.costello@nhs.netTW / X: @Voicedoctor_uk Congress season is well underway around the world – with all that’s going on, it’s hard to keep track...
IL-25 and nasal polyps, another target
Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...
Applying ‘Sal classification’ to parotid cytology to replicate the success of the Thy classification system
The usefulness of the Thy classification in thyroid gland disease has led to attempts to generate a similar cytology classification for parotid lesions. However, the accuracy of fine-needle aspiration cytology in salivary gland disease is more variable because of the...
Multisystem pathology in refractory otitis media with effusion
Recurrent middle ear effusion is a common problem and so is rhinosinusitis with polyposis. It is not often thought that the problem could be linked to multisystem pathology, such as eosinophilic granulomatous with polyposis. Therefore, repeated grommet insertions and surgical...
Biopsy sites with a diagnosis of pemphigusand mucous membrane pemphigoid
This is a systemic review and met-analysis to critically evaluate optimal biopsy site for patients presenting with pemphigus or mucous membrane pemphigoid. Historically, diagnosis is made if H&E staining direct immunofluorescence and serological testing of auto-antibodies. Direct immunofluorescence has been...
Outcomes and progress of a well-designed one-stop head and neck lump clinic
With increasing caseload of head and neck cancer and the fact, as reported by UK Government in October 2024, that over half of these cases are diagnosed at an advanced stage, the need for early diagnosis and prompt management is...In conversation: Cesare Piazza and Giuseppe Spriano
Declan Costello catches up with the presidents of two important meetings taking place in Italy in June 2023 to discuss the highlights.
Macrolinguistic assessment in early Alzheimer’s disease
Deficits in language production like word finding difficulty, and lexical-sematic impairment have been documented early in the course of Alzheimer’s disease (AD). According to the authors, the current language assessment methods used in AD patients do not account for macrolinguistic...Genetics WG4. Improving diagnosis and drug development through the genetic understanding of tinnitus subtypes: a TINNET endeavour
Christopher R Cederroth and Jose Antonio Lopez-Escamez explain how progress is being made to investigate the contribution of genetic factors to tinnitus, including a subtype of ‘extreme’ tinnitus in Ménière’s disease. Genetics WG4 is working towards determining the genetic basis...The European TINNET COST Action BM1306
Winfried Schlee describes how a major European funding award is bringing together experts who are committed to collectively developing a better understanding of tinnitus. This work is vital if we are to pioneer effective treatments for the condition in its...Utilisation of cortical auditory evoked potentials in the paediatric population
Introduction Early identification of hearing loss in infants followed by prompt intervention is well established as the key to maximising the development of speech, language and psychosocial skills. Many countries have already adopted early hearing detection and intervention (EDHI) programs,...
