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Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

The changing spectrum of cancer of the oropharynx: dilemmas and future directions

The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....

Aetiology, investigation and acute management of sudden sensorineural hearing loss

The cause of a single sided sensorineural hearing loss has a wide variety of aetiologies. This review, by Edwin Halliday, looks specifically at the differential diagnostic causes of a sudden sensorineural hearing loss, the relevant investigations and the management should...

Will it ever happen?

Audiology is a rapidly evolving field, with many exciting developments on the horizon. David Baguley identified some topics of interest, and asked some international experts ‘will it ever happen?’ Gene therapy for deafness After years of development, gene therapy for...

Endoscopic Dacryocystorhinostomy

Epiphora, or abnormal tearing, occurs because of blockage in the lacrimal drainage system, which impairs normal tear channeling into the nose. Dacryocystorhinostomy (DCR) is used to treat patients diagnosed with lacrimal sac or nasolacrimal duct obstruction (NLDO). External DCR was...

The ‘bus stop’ incision for bone-anchored hearing aid placement: a step-by-step approach to soft tissue preparation

There have been many descriptions of soft tissue preparation in the era when subcutaneous tissue was routinely removed with the Nijmegen technique [1] or with the dermatome [2]. More descriptions continue to evolve with the advent of tissue preservation techniques,...

New ventilation technique FCV: improvement for patient, anaesthetist/intensivist and surgeon

Per-oral surgical access to the larynx can be hampered by the presence of an endotracheal tube. Various systems have been developed for tubeless ventilation, but these all carry a risk of aerosolisation of secretions with obvious inherent risks. We hear...

A medical student’s perspective on the future of obstructive sleep apnoea management

Obstructive sleep apnoea remains an immensely challenging condition to treat. Many treatments have been used over the years, but no single management strategy has proven significantly better than the others. We hear about some technological innovations in the field of...

Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...

Practical training courses for otolaryngology trainees

In this extended Trainee Matters, it’s a pleasure to present a trio of excellent articles with a theme of practical training courses for otolaryngology trainees. Miss Rachel Edmiston, Professor Nirmal Kumar and colleagues have written a valuable guide to setting...

2014: Are today’s implantable devices better than conventional solutions for patients with conductive or mixed hearing loss?

Patients with conductive or mixed hearing loss become candidates for amplification when reconstructive surgery is not viable. Three common amplification options are conventional acoustic devices, such as behind-the-ear devices (BTEs), (implantable) bone-conduction devices and active middle ear implants. The goal...