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The changing spectrum of cancer of the oropharynx: dilemmas and future directions

The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....

The polyp shrinker

Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...

Audiological and psychological consequences of single-sided deafness

The loss of sound input from one ear has a significant impact on our perception of our acoustic environment. This impact is compounded in adverse listening conditions. Rachel Knappett’s article explores the audiological impact of this hearing loss and the...

Ida Institute tackles clinician burn-out

Founded in 2007, Denmark’s Ida Institute is dedicated to the health of people with hearing loss. Its new four-part course, however, is aimed at another group: the medical professionals whose jobs can compromise their own health.

What is Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE)?

THRIVE is a physiological mechanism for oxygenating and ventilating patients who are under general anaesthesia and who have diminished or absent respiratory effort [1]. Classical ventilation requires bulk flow of gases into and out of the lungs driven by chest...

Do you feel me? Emotional processing post-traumatic brain injury

Traumatic brain injury (TBI) accounted for just under three million accident and emergency admissions in the US in 2013, with common causes including falls, traffic accidents and assaults. Difficulties processing and expressing affective communication is a common sequela of TBI...

Pediatric Otolaryngology Practical Clinical Management

The pleasing thud of this book dropping through my letterbox was tempered by mild anxiety. I’d just accepted an adult ENT job with a paediatric on-call, and my trusty Graham, Scadding and Bull was nearly a decade out of date....

Electronystagmography and Videonystagmography ENG / VNG

This book provides a good reference for anyone starting out in the field of balance assessment, and would be a useful book in any balance assessment clinic as a source of information from anatomy to test interpretation. Anatomy and physiology...

Scientific Foundations of Audiology: Perspectives from Physics, Biology, Modeling and Medicine

Scientific Foundations of Audiology – Perspectives from Physics, Biology, Modeling and Medicine is a unique textbook which discusses a wide range of state-of-the-art topics in hearing, vestibular and brain science. The editors purport that this book is geared towards doctoral...

Basic Audiometry Learning Manual - Third Edition

Unfamiliar with the first and second editions, it was a pleasure to review the third edition of the Basic Audiometry Learning Manual. As with many of such books available to the market, and as one would expect, there is a...

New MRI technique assesses treatment response in skull base osteomyelitis

This paper describes another useful imaging technique to monitor Necrotising Otitis Externa (NOE). Echoplanar diffusion weighted magnetic resonance (DW MR) shows high signal on the ‘ADC map’ with active disease and this reduces in signal intensity as symptoms improve. This...

A psychophysical perspective on single-sided deafness and its treatment by cochlear implants

Bob Carlyon gives us a psychophysical perspective on the hearing benefits that can and cannot be achieved for patients with single-sided deafness with a cochlear implant, and discusses some of the challenges in maximising the effectiveness of the treatment. He...