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Risk factors for TORS treatment failure in HPV-related oropharyngeal cancers
HPV-related squamous cell cancers are an increasingly common cause of malignancy in the oropharynx. There is evidence that these cancers are associated with a significantly improved overall survival compared to conventional HPV-negative tumours. The optimal treatment for such cancers is...Working with people with hearing loss and dementia
A member of the SENSE-Cog team in the UK, Dr Littlejohn provides an overview of multidisciplinary recommendations for diagnosis, management and care of older adults with hearing loss, vision loss and dementia. She underscores how consideration of hearing status when...
CRSwNP initiation, not always an interleukin fault
CRSwNP, similar to asthma, is an inflammatory disorder (type II) with eosinophilia and raised IL-5 and IL-13. Inflammation in CRSwNP is thought to be started by IL-25, IL-33 and thymic stromal lymphopoietin (TSLP), all of which form an important part...The Graham Fraser Foundation
Graham Fraser (1936-94) was a pioneering otolaryngologist, in whose memory the Graham Fraser Foundation was set up, and an eponymous annual lecture and a travelling fellowship in otology were established. It’s an honour to profile the Foundation in this extended...Optical cochlear implants: recent progress toward light-based hearing restoration
Optical cochlear implants combine optogenetics and light-based hardware to overcome limits of electrical CIs, promising sharper frequency resolution and more natural hearing. Cochlear implants (CIs) are among the most successful neuroprosthetic devices in modern medicine, restoring speech perception to hundreds...Minimally invasive techniques for benign salivary gland obstruction
Salivary gland obstruction is a common condition – it is recognised by a complaint of intermittent meal-time swelling of the affected salivary gland and can be accompanied by recurrent infections. Imaging can identify the nature and location of an obstruction...
