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Updates on current evidence for biologics in chronic rhinosinusitis

For a comparatively short piece, this article manages to pack in a lot of important information about a complex emerging area of rhinology – immunologically targeted therapy (biologics). Immunologically targeted therapy is a rapidly progressing and expanding domain which is...

Eosinophilic complications during dupilumab therapy

Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...

How the earwig got its name

What are earwigs, and how are they connected with the ear? Amr Abdelhamid explains the etymology, myths and beliefs behind the pesky creature with the otological name. Earwigs are harmless insects of the order Dermaptera that are amongst the most...

The challenges in the risk stratification of thyroid nodules and cancers: the role of molecular testing

Around the world, molecular testing is becoming more widely used to personalise the management of thyroid nodules. Thyroid nodules are relatively common. They are palpable in ~5% of the population, while high-resolution ultrasound (US) incidentally finds them in 19–68% of...

Guillotines from Joseph‑Ignace Guillotin to Greenfield Sluder

Joseph‑Ignace Guillotin. The politician and physician Joseph-Ignace Guillotin (1738-1814) was so disgusted by brutal head and shoulder injuries sustained in ‘failed attempts’ by drunken axe-wielding executioners during the French Revolution that he and surgeon Antoine Louis (1723-1792) advocated not only...

World Hearing Day 2022: WHO launch webinar goes online

The World Health Organisation (WHO) took the opportunity of World Hearing Day on 2 March to announce three hearing-loss initiatives. As well as establishing a global standard for safe listening entertainment venues, it published a related handbook for implementation of safe listening and released a media brief for journalists.

ICG in ENT surgery

The use of fluorescence imaging is well established in the medical sphere, forming an essential arm of medical diagnostics with liver function, ophthalmic angiography, and assessment in cell biology with fluorescence microscopy. Fluorescence imaging in surgery, however, is an evolving...

CO2 Laser Dohlmans: Does It Still Have A Role In Pharyngeal Pouch Management?

Background The commonest active management of a pharyngeal pouch is the division of the “interparty” wall using a stapling device [1, 2]. The technique is relatively straight forward to perform and theoretically should have less complications than other techniques such...

Clinical Otology, Fourth Edition

Seven years after publication of the third edition, this latest edition of Clinical Otology brings the reader right up to date with developments within this constantly evolving field. Maintaining the same format as the previous edition, it concentrates on four...

The totally implantable cochlear implant

*The authors are in alphabetical order – both authors are first authors on this publication A groundbreaking fully implantable cochlear implant marks the start of a new era in hearing restoration – discreet, continuous and free from external hardware. The...

Nasal and aural foreign body removal: another technique for a common problem

Trying to remove foreign bodies from the ears and noses of children is something we have all struggled with at various times. Many people have their own top tips, and here Oliver McLaren and Alexander Walkden describe an ingenious way...

Targeting the microbiome in chronic rhinosinusitis

Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...