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Postoperative radiation in early stage oropharyngeal squamous cell cancer (OPSCC)

There is significant variation in treatment strategies for OPSCC between units. This is largely due to unanswered questions which continue to exist beyond the published literature. We know that human papilloma virus status has a significant influence on prognosis but...

Impact of the updated cancer staging system on HPV-positive disease

The AJCC cancer staging manual was updated in 2017 (8th edition). It is used in the MDT setting for planning treatment and assessing prognosis for individual patients, and is also widely used internationally in clinical trials. Unlike previous iterations of...

Advances in surgical innovation for head and neck cancer

This article reviews current advances in surgical treatment of head and neck cancers such as sentinel node biopsy, stereolithic modelling, transoral robotic surgery and intra-operative imaging of tumour margins. Sentinel node biopsy has been found to be especially useful for...

Long-term swallowing function in bilateral vocal cord immobility

Vocal cord immobility is the second most common abnormality of the larynx in the paediatric population. The team from New York aimed to characterise the long-term swallowing function in a cohort of patients with bilateral vocal cord immobility over a...

Expanding the role of FNA in thyroid nodule decision-making

Papillary thyroid cancer, the commonest histological type, has been extensively reported as having BRAF proto-oncogene mutations (most commonly the V600E mutation). There is great interest in BRAF as a molecular marker, particularly as a prognostic factor that may guide the...

Recovery of vestibular function after vestibular neuritis

It is well known that recovery from vestibular neuritis (VN) is not solely mediated through central vestibular compensation, but also at the peripheral level. The authors conducted a prospective study to track the dynamic changes in recovery from vestibular neuritis...

How effective is vestibular rehabilitation in bilateral vestibular failure?

In patients with bilateral vestibular hypofunction (BVH), the outcome of vestibular rehabilitation is mixed. The aim of the study was to identify factors associated with outcome of vestibular rehabilitation (VR) in patients with BVH. A retrospective case notes review identified...

Adenoid cystic carcinoma – insights from a national database

Adenoid cystic carcinoma (AdCC) is a rare cancer of the salivary glands that accounts for approximately 1% of all head and neck malignancies. Hallmarks of this cancer type include a predilection for perineural infiltration, a prolonged clinical course with late...

Clinicopathological features of follicular variant of papillary thyroid carcinoma

The follicular variant (FV) of papillary thyroid carcinoma (PTC) is characterised by the presence of nuclear features of PTC together with a follicular growth pattern. It is currently reported to make up 11.8% to 53.3% of all PTC cases. It...

Changing perceptions in head and neck cancer management caused by quality of life issues

Sir Felix Semon was an outstanding clinician and exceptional laryngologist. The money raised by donations from his colleagues on his retirement in 1909 was used to establish the London University’s Semon Lecture. Semon’s Obituary in the BMJ, reads: “In Semon's...

Medical and surgical management of performing vocalists

Dr Steven Zeitels is widely recognised as the foremost laryngologist of his generation. He has been at the forefront of innovation for 25 years, and has treated innumerable high-profile singers, most recently Sam Smith and Adele. Here, he gives us...

Knowledge is power: the power of mobile technologies to enhance hearing-related knowledge

In recent years, the widespread use of smartphones has made it increasingly possible to improve knowledge, understanding and delivery of hearing healthcare. Melanie Ferguson tells us about the advances in mobile-health applications. Think back to five years ago - what...