You searched for "genomics"

313 results found

Sulcus vocalis in patients attending voice clinics: A retrospective study

Sulcus vocalis was first described by Giacomini. This includes a variety of anatomic indentations of the vocal fold, ranging from shallow longitudinal furrows to deep vocal cord pits. This retrospective study was conducted at King Saud University between 2006 and...

A higher aspiration for fine needles

Fine needle aspiration biopsy (FNAB) has aided in the diagnosis and management of thyroid nodules for decades. Now a rapid evolution is hoped to benefit an increasing cohort of patients with small nodules and non-diagnostic investigations. This review discusses the...

Surviving oropharyngeal squamous cell carcinoma – does subsite matter?

Human papilloma virus (HPV) status is a known prognostic factor in oropharyngeal squamous cell carcinoma (OPSCC). The eighth edition of American Joint Cancer Committee (AJCC) has modified the TNM staging to reflect this. However, subsite as an independent prognostic factor...

Genetics of IP-III

The authors provide a literature review of the genetic basis and clinical features of incomplete partition (IP)-type III. The condition is seen typically in males and is due to mutation in the POU class 3 homeobox 4 (POU3F4) gene which...

The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies

Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...

Reducing hierarchy for individuals and teams across ENT

Alexander Pope said that “to err is human”, but medical errors can have serious consequences. How can better communication minimise the risk of them occurring in the first place? Allowing all members of the surgical team to feel empowered to...

Feeling like a fraud — imposter syndrome: what it is and what to do about it

Have you ever been plagued by feelings of incompetence despite evidence to the contrary, then this article is for you. Dr Dunay Schmulian provides insight into imposter syndrome and what to do about it. Excerpt 1 Senior Audiologist: That was...

A person-centred approach to telehealth

“The time when telehealth was a remote, abstract concept has come to an end”. Deborah Ferrari and Lise Lotte Bundesen discuss how to advance person-centred care in hearing rehabilitation through online tools and training. The time when telehealth was a...

The importance of hearing aid validation in infants with hearing loss

Hearing aid validation requires that speech discrimination be measured, yet there are no validated methods of measuring speech discrimination in infants and toddlers. Prof Uhler describes two related approaches that are showing promise. Speech discrimination is the gold standard for...

Personal perspective of a hearing aid user: In conversation with Alistair Cruickshank

Alistair Cruickshank explains how he has embraced technological changes to improve his day-to-day listening experiences as a hearing aid user. He explains the importance of experimenting and trying out different approaches and how much he values working closely with his...

Observations and ruminations - a week of collaboration and learning in Ghana

A week of surgical exchange in Ghana reveals the power of collaboration, resilience and mutual learning in advancing global ENT care. Isabelle JM Williams. Isabelle’s perspective It was a Saturday lunchtime at Heathrow airport, terminal 3. Professor David Howard, Miss...

Imaging tinnitus

Tinnitus is a common sensation with a reported prevalence of 7-32%. The British National Study of Hearing recorded that 10% of adults suffered from prolong spontaneous tinnitus, and approximately a quarter of these are subsequently referred to hospital for investigation...