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Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

The workplace environment and doctors’ health (ENT)

It is well established that doctors have higher levels of stress, depression and suicide than the general population [1] and most other professional groups (Figure 1 illustrates the factors that can make us ill). In addition they have high levels...

Thyroid ultrasound elastography: does nodule stiffness predict malignancy?

Approximately 50% of the general population has a thyroid nodule while 5-15% of these are malignant [1]. A major challenge, therefore, is how to detect the malignant nodules for appropriate, timely treatment and avoid unnecessary, costly investigations for the remainder....

NHS collaboration and partnership with the pharmaceutical and medical devices industries

Historically the relationship between industry and the NHS has been a cautious one. Both sides have typically worked with only partially disclosed agendas, under a pervading fear of finding themselves on the wrong end of a win-lose negotiation. Things have...

Surgical management of sleep disordered breathing

Snoring and sleep-disordered breathing are often described as multi-level problems, and different surgical procedures are required to treat the various sites of airway narrowing and/or collapse. Jonathan Hobson gives us an eloquent run-through the various options available to the ENT...

BACO 2015: Meet the Key Brits

The triennial BACO is always a feast of academic and social activity – and BACO 2015 promises to be as busy as ever. We hear from three of the key British speakers who are making big contributions to this year’s...

Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

Robotic head and neck surgery: current state of the art and future innovations

Technology and innovation has provided modern head and neck surgeons with successive generations of robotic surgical systems, fibre-optic lasers, and novel tools which have ushered in a new era of minimally invasive surgery for tumours of the pharynx and larynx....

The role of macrolide antibiotics in chronic rhinosinusitis

The use of long-term antibiotics in the treatment of chronic rhinosinusitis is a contentious issue, not only because of the increasing problem with antibiotic resistance but also because of the potential cardiac risks, including sudden death. In this article, Anders...

Vocal cord paralysis: an update

The management of unilateral vocal cord paralysis has changed in the last few years: this has largely come about as a result of improvements in technology, meaning that medialisations are quicker and easier to perform than previously. This article will...

Taking life by the throat

Patients suffering with problems with their voice, airway and/or swallowing can find their symptoms immensely distressing, and their care places a huge burden on healthcare systems. We hear from a world-leading laryngologist on current and future directions. Field of interest...