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Eosinophilic complications during dupilumab therapy
Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...What is Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE)?
THRIVE is a physiological mechanism for oxygenating and ventilating patients who are under general anaesthesia and who have diminished or absent respiratory effort [1]. Classical ventilation requires bulk flow of gases into and out of the lungs driven by chest...Deaf scholar is UK first
The first deaf scholar ever to achieve full professor status in the field of deaf studies and sign language studies in the UK has been announced at Heriot-Watt University in Edinburgh.Radiology and sinus disease: “the ever-evolving landscape”
Computed tomography (CT) remains the imaging modality of choice in assessment of patients with symptoms of chronic rhinosinusitis resistant to conservative treatment. In the last 10 years, CT technology has seen significant advances with the development and integration of multi-detector...
Management of smell and taste disorders – A practical guide for clinicians
This textbook with 240 pages is well laid out, very well illustrated including colour photographs and has excellent summary boxes at the end of individual sections. Up to one fifth of adults have some form of olfactory dysfunction and as...
How young is too young for tympanoplasty?
This paper presents the largest series of pre-school age children undergoing tympanoplasty compared with older children. The authors have collected much prospective data on 259 children undergoing 284 surgeries so were able to perform multivariate analysis. The age groupings of...
Do you feel me? Emotional processing post-traumatic brain injury
Traumatic brain injury (TBI) accounted for just under three million accident and emergency admissions in the US in 2013, with common causes including falls, traffic accidents and assaults. Difficulties processing and expressing affective communication is a common sequela of TBI...
How can we manage children with poor speech discrimination but with normal audiogram
We often come across children and young adults brought in for consultation for suspected hearing loss and having hearing difficulty in noisy backgrounds but who often have normal audiograms. Such patients are suspected to have auditory neuropathy. The term auditory...
Benign positional paroxysmal vertigo manoeuvres in children and adolescents: a systematic review
In this paper of Saniasiaya et al, the literature review is conducted in accordance to the PRISMA consensus, aiming to investigate the outcomes of canalith repositioning manoeuvres (CRM) to treat benign paroxysmal positional vertigo (BPPV) in a paediatric and young...
