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1292 results found

Unanswered questions in adult ototoxicity associated with platinum-based chemotherapy

Do the potential side-effects on hearing and tinnitus need to be a ‘necessary evil’ of platinum-based chemotherapy? How strong is our evidence base when offering advice to patients and fellow clinicians? David Baguley and his team from the University of...

Swallowing outcomes following partial laryngectomy: objective assessment and pre-operative predictive factors

Partial laryngectomy constitutes one of the treatments for early stage glottic carcinoma (i.e. T1N0 and T2N0) in specialised centres. Over the years, several partial laryngectomy and reconstruction techniques have been described in the literature. The choice of technique depends on...

An update on laryngeal reinnervation

Laryngeal paralysis remains very difficult to treat, but reinnervation offers many attractions. Laryngeal paralysis presents a unique and varied problem that requires a patient centred approach and a range of treatment options depending on laryngeal and patient factors. There is...

Thyroid dysfunction and Meniere’s disease: is there a relationship?

The set of symptoms described as Meniere’s disease may have several causative factors. Timothy Hain and Patthida Maroongroge look for a relationship in the literature between Meniere’s disease and hypothyroidism. Meniere’s disease (MD) affects around two in 1000 people and...

Staphylococcus aureus as a cause of refractory chronic rhinosinusitis

Staphylococcus aureus has long been linked to chronic rhinosinusitis, particularly recalcitrant cases. In this article, Alkis Psaltis describes how newer techniques have shown higher rates of S. aureus infection than were previously thought, and explains how the bacteria are able...

HPV and ENT; should we vaccinate boys?

David Black and Charlie Hall reiterate Vin Paleri’s pleas for a common sense evidence-based approach by those who allocate healthcare resources to the now urgent issue of HPV-related disease. They discuss the merits of different vaccines and the need for...

Supracricoid laryngectomy revisited

In this article, the authors report on the long-term (five- and 10-year) survival, local recurrence rate and cause of death in a cohort of 46 patients with T3M0N0 glottic carcinoma undergoing supracricoid laryngectomy. The five- and 10-year survival were 78%...

Adolescence, drug use and body image

Teenagers are notoriously conscious of how they are perceived by others. Dr Saraiva and colleagues explain how this can lead to problems with substance abuse for both boys and girls, and discuss the different substances they may encounter. Adolescence is...

In conversation with Prof Helge Rask-Andersen: on cell regeneration and treatment of human deafness

Helge Rask-Andersen, head of the inner ear research laboratory at the University of Uppsala in Sweden, has many achievements to his name. He was made an Honorary Member of ENT UK earlier this year. Gerry O’Donoghue caught up with him...

Neurological idiopathic disease: a shared journey for NASA and medicine

Whilst Southampton can’t really be described as an extreme environment, experiments carried out in the city have certainly been taken out of this world. Robert Marchbanks discusses one of the associations between Southampton, The International Space Station and tympanic membrane...

Microneedles enable inner ear precision medicine

Developing safe, reliable and efficient ways to deliver therapeutics into the cochlea is a key challenge. In this article, the authors share their work to develop microneedles to address this challenge. The era of precision medicine of the inner ear...

In conversation with Prof Helge Rask-Andersen: on cell regeneration and treatment of human deafness

Helge Rask-Andersen, head of the inner ear research laboratory at the University of Uppsala in Sweden, has many achievements to his name. He was made an Honorary Member of ENT UK earlier this year. Gerry O’Donoghue caught up with him...