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Tympanostomy tubes outcomes by tympanic quadrants- a meta-analysis
Tympanostomy tube (TT) insertion is one of the most common ENT procedures, resulting in millions of TTs being implanted per annum and occurring complications that need to be addressed. Premature TT extrusion (PTTE) is a well-recognised such complication, affecting almost...
Long-term curative effects of microvascular decompression for hemifacial spasm
This article describes results of a multicentre prospective trial performed to evaluate long- and short-term outcomes and complications of patients who underwent microvascular decompression (MVD) for hemifacial spasm (HFS). The surgeries were performed by surgeons with more than 15 years...
Possible correlation of ABR changes with prognosis in sudden sensorineural hearing loss
A sensorineural hearing loss (SNHL) of 30dB or more affecting at least three frequencies and occurring over less than three days is classified as ‘sudden’ SNHL (SSNHL). Treatment is urgently undertaken with systemic and/or intra-tympanic steroids, and ijn some cases...
Salvage surgery vs. repeat stereotactic radiosurgery for progressing vestibular schwannomas
This large multicentre case series of patients treated twice with stereotactic radiosurgery (SRS) for progressing vestibular schwannomas (VS) is reported by the International Gamma Knife Radiosurgery consortium. Progression of tumour growth after primary SRS is rare but does occur. Complications...
CRSwNP initiation, not always an interleukin fault
CRSwNP, similar to asthma, is an inflammatory disorder (type II) with eosinophilia and raised IL-5 and IL-13. Inflammation in CRSwNP is thought to be started by IL-25, IL-33 and thymic stromal lymphopoietin (TSLP), all of which form an important part...
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
Association of childhood OME with obesity
Many factors influence the development of otitis media with effusion (OME) in children, some of them being increased plasminogen factor inhibitor (PAI-1) levels, eustachian tube obstruction and gastro-oesophageal reflux. These factors are also associated with obesity. Sixty children with mean...
Neck dissection in adenoid cystic carcinoma is a risk worth taking?
This paper from Stanford University presents impressive figures to guide the debate on the extent of surgical management in adenoid cystic disease. Adenoid cystic carcinomas present a particular problem in that they can recur even after 20 years. They have...
Does endoscopic tympanoplasty give better results than a conventional approach?
This is a retrospective review looking at two groups of patients who had undergone middle ear surgery for chronic otitis media (perforation, retraction pocket/cholesteatoma) either open or endoscopic. Four hundred and five patients underwent open ear surgery and 501 endoscopic,...
Paediatric pituitary surgery - is it lagging behind?
Endoscopic sellar surgery, especially for adenomas, is a relatively safe, straightforward surgery with (mostly) reproducible results and few complications. However, the evolution of pituitary surgery was a long process, starting from open/transfrontal approaches all the way to transsphenoid to the...
The microbiological environment of the paranasal sinuses
This article reviews the ecology of the sinuses and tries to make sense of the confusing literature on the subject. This covers the details of molecular studies, particularly those which attempt to differentiate normal sinuses from those in patients with...
