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Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

Resolving dysphagia – can we distinguish mild dysphagia from no dysphagia?

Many patients with dysphagia following neurological events can and do experience a resolution of their swallowing difficulties, sometimes without any intervention. However, it is challenging for clinicians to distinguish mild dysphagia from no dysphagia. The question of where to draw...

Nasal polyps, does size matter?

This study from Germany investigates the correlation between nasal polyp size and return of olfactory function following endoscopic sinus surgery. Olfaction is affected more in patients with CRSwNP than with CRSsNP and the best chance of smell recovery occurs in...

Is there an association with cognitive impairment and hearing loss in a developing country?

Hearing loss (HL) is the third leading chronic health condition among older adults. Most studies investigating HL and cognition have been performed in high-income countries. Risk factors for dementia (eg. hypertension, midlife hearing loss, obesity and physical inactivity) are more...

Electrocochleography and cochlear implants programming

Cochlear implants (CIs) often are the only option for people with severe to profound sensorineural hearing loss to be able to hear. Therefore, effective CI programming seems very important, especially in children who are still developing their speech. Using acoustic...

Global incidence of sporadic vestibular schwannoma

The incidence rate of sporadic vestibular schwannoma (VS) has commonly been quoted as one in 100,000. However, since the advent of screening for asymmetrical hearing loss and increased availability of modern MRI scanning, more recent studies have shown the incidence...

Diagnostic features of acute invasive fungal sinusitis

Acute invasive fungal sinusitis (AIFS) is a rare but frequently lethal condition, commonly associated with a high morbidity among those that survive. It has gained recent media attention on account of its increased incidence following infection with (and treatment for)...

How common is dysphonia and dysphagia after cardiac surgery?

Patients undergoing cardiac surgeries, such as coronary artery bypass (CABG) and valve operations, are usually informed that there may be some risk of laryngeal complications that could result in a dysphonia or dysphagia. This may be due to factors including...

An inherited platelet disorder in a post- tonsillectomy haemorrhage

Unexplained bleeding after any surgery is least desirable and to identify a cause for this preoperatively can be a very useful safeguarding measure. By looking for inherited platelet disorders in patients who bled after tonsillectomy, the authors of this publication...

Reflux, a pre-disposing factor in paediatric OME?

It is almost 20 years since the Lancet publication by Tasker et al describing gastric juice in the glue ear of children. This paper attempts to look at the body of literature which has focused specifically on the clinical association...

Dysphagia following intubation during the COVID-19 pandemic

Dysphagia is a known sequela of mechanical ventilation and intubation. About a third of patients discharged from hospital after acute respiratory distress syndrome present with dysphagia. The authors of this review have considered the implications for patients intubated due to...

Quality of life in adolescence

Adolescence can be a difficult time and the added complexity of a hearing loss can exacerbate feelings during this period. In the literature, there are mixed findings that show while some children with hearing loss score poorly on some aspects...