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Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?
Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...
Role of intratympanic corticosteroid for treatment of Bell’s palsy and Ramsay Hunt syndrome
Acute peripheral facial palsy occurs annually in 30 in 1,000,000 individuals in the general population. Bell’s palsy and Ramsay Hunt syndrome account for about 70% of cases of peripheral facial palsy. They are believed to be caused by viral reactivation...
Ramifications of the pandemic on acute paediatric mastoiditis: a national UK audit
Acute mastoiditis is a common presentation in the paediatric population across ENT services worldwide. An initial expectation of a rise in the numbers of acute mastoiditis associated with the initial findings of SARS-CoV-2 (COVID-19) virus presence in middle ear in...
Assessing the impact of e-cigarette smoke on the vocal fold
While the use of electronic-cigarettes (e-cigs) is increasing rapidly, little is known about the effects this has on the health of vocal fold. In this translational research study, authors compared the effects of e-cig vapour and cigarette smoke on an...
Hearing aids to improve balance in the elderly?
Patients with hearing loss have been found to be more likely to develop dementia. Hearing loss is also associated with poor balance and higher risk of falls, especially in the elderly population. There is increasing evidence that treating hearing loss...
Recurrent facial palsy
Recurrent facial palsy is relatively rare, and its clinical features are not well known. The authors set out to investigate this further by undertaking a retrospective study of patients with recurrent facial palsy over a 14-year period. Only Bell’s palsy...
Success of butterfly myringoplasty in myringosclerosis
Butterfly inlay myringoplasty is a simple surgical technique used in the repair of tympanic membrane perforation. The authors evaluated the effects of myringosclerosis on the success of surgery by reviewing demographic data, perforation size and hearing outcomes of patients undergoing...
Active surveillance for papillary thyroid cancers – what is the risk of progression?
Papillary thyroid cancers (PTCs) are generally considered to be indolent malignancies with favourable outcomes. Active surveillance (AS) has consequently been trialled as a management option for small PTCs with no evidence of regional lymph node involvement, especially papillary thyroid microcarcinomas...
A systematic review of adjunctive probiotic therapy in the management of chronic rhinosinusitis
It is generally understood that administering substances containing live microbiologically active micro-organisms (probiotics) enhances the treatment of chronic rhinosinusitis. Probiotics manipulate and rebalance the alterations occurring in the local microbiome in chronic rhinosinusitis patients. This results in propagation of healthy...
Hear me out – tiny steroid implants for fighting meningitis-induced deafness
Sensorineural hearing loss is the most common neurological complication of pneumococcal meningitis. Bacterial infiltration into the inner ear triggers inflammation, leading to cochlear fibrosis and sclerosis – damage that, in over a third of cases, affects both ears. Current Infectious...Supporting patients with chronic dizziness and investing in vestibular research
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