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Brown classification of a maxillary defect and prognosis
This is a retrospective study from Peking over the 10-year period, 2000-2010, for 137 patients with maxillary squamous cell carcinoma assessed. The overall survival rate was comparable with other studies at 64.8%. The most common Brown maxillary defect was 2b...
Treatment outcomes and dose rate effects following gamma knife stereotactic radiosurgery for vestibular schwannomas
Gamma knife radiosurgery (GKRS) is one of the definitive stereotactic radiotherapy treatment modalities for vestibular schwannoma (VS) management. Its efficacy depends on the cobalt-60 source which has a half-life of 5.26 years. According to the study authors, the actual rate...
Follow-up of NF2 patients with ABRs, SDS and MRI
Hearing loss is one of the earliest manifestations in vestibular schwannomas with 60% of the patients having high frequency loss. Several metabolic and mechanical factors influencing the cochlea and cochlear nerve have been implicated in the hearing decline noted in...
Is a chest x-ray necessary in making urgent referrals for suspected head and neck cancer?
The article presents an audit on urgent referrals for suspected head and neck cancer in 2144 patients. Only 8.6% of cases proved positive for head and neck cancer. The Scottish Referral Guidelines were adhered only in 55.1% of cases. Interestingly,...
Modern surgical treatment for obstructive sleep apnoea indicate suppression of inflammatory cytokines
This study comprises 57 patients, 29 of which were treated by anterior palatoplasty procedure, expansion sphincter pharyngoplasty and submucosal minimal invasive lingual excision techniques and 27 by CPAP therapy. Parameters to determine success were AHI, VAS score, ESS score, mean...
An algorithm to distinguish between distant metastases and metachronous lung primary in patients with HPV-related oropharyngeal cancer
Distinguishing between distant metastases of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) and metachronous primary lung squamous cell carcinoma (SCC) is important as it has implications for treatment, prognosis counselling, and registry data. Although p16 immunohistochemistry (p16 IHC) is widely accepted...
Rhinology and 3D printing
3D printing has increasing applications in rhinology, for instance to create patient-specific preoperative models for procedure planning, including designing a template for reconstruction planning following tumour resection, patient consultation and customised prostheses. The authors focused their review on the role...
A comparison between ultrasonography-guided drainage with open surgical drainage of deep neck space abscesses
A comparison between ultrasonography-guided drainage with open surgical drainage of deep neck space abscesses Neck space abscesses are common; conventional drainage involves intra-oral or extra-oral approaches. The former can compromise the airway and the latter can cause neurovascular injuries, scarring...
Should we reconsider induction chemotherapy in advanced stage laryngeal cancer?
Use of chemo-radiotherapy for advanced laryngeal cancer led to a major shift in treatment as an alternative to total laryngectomy. Despite widespread adoption of chemoradiotherapy, survival rates have not improved and the original premise of matching neoadjuvant chemotherapy tumour response...
Previous radiotherapy does not cause worse outcomes in patients with differentiated thyroid cancer
Radiation exposure from nuclear incidents, especially in childhood, is known to increase the risk of thyroid cancer. This large retrospective study from the Memorial Sloan Kettering Cancer Centre sought to determine if thyroid cancers in patients with prior exposure to...
Sellar surgery – when to prepare for repair
Endoscopic sellar surgery, especially for adenomas, is a relatively safe, straightforward surgery with (mostly) reproducible results and few complications. One of the commonest complications is the creation of a CSF leak with the subsequent need for repair (there is usually...
