You searched for "trial"

1291 results found

Variations in obstructive level with increasing depth of sedation in DISE

This study highlights some of the controversies surrounding DISE (Drug Induced Sedation Endoscopy, or otherwise known as sleep nasendoscopy in the UK). On one hand it provides some evidence that the BIS (BiSpectral Index), recordings of patients while they are...

Congenital cytomegalovirus causing deafness in children: an update

Congenital CMV is the leading non-genetic cause of sensorineural hearing loss in children. Keith Trimble draws our attention to this and gives a comprehensive guide on diagnosis and treatment. Congenital cytomegalovirus (cCMV) infection is common, affecting 1% of all newborns,...

Prednisolone and/or acyclovir for Bell’s palsy

Landmark Paper: Sullivan FM, Swan IRC, Donnan PT, et al. Early treatment with prednisolone or acyclovir in Bell’s Palsy. N Engl J Med 2007;357(16):1598-607. Facial nerve paralysis as a consequence of Bell’s palsy can result in devastating long-term effects on...

COACH calls for participants

The Nottingham Clinical Trials Unit has renewed a call for volunteers to take part in its COACH programme. The UK-wide trail aims to generate evidence about the use of hearing aids.

Standardising outcome measures in chronic rhinosinusitis

This international paper, involving the foremost rhinology departments worldwide aims to provide a standardised, agreed core outcome set for chronic rhinosinusitis, which has been designed to facilitate future meta analyses of published work in systematic reviews. Stakeholders included patients, ENT...

The James Lind Alliance – involving patients and their health professionals jointly in setting priorities for research

In a world of patient-reported outcomes and patient-centred care, patient-centred research must also be considered. That is where the James Lind Alliance (JLA) comes in, as Caroline Whiting explains below. Through Priority Setting Partnerships (PSPs), it allows patients, their carers...

Office-based intralesional corticosteroids injections for subglottic stenosis. Is it effective?

Subglottic and proximal tracheal stenosis in adults has three main aetiologies: (a) prolonged endotracheal intubation; (b) idiopathic; (C) rheumatologic related. Endoscopic dilation is the mainstay treatment strategy for subglottic and proximal tracheal stenosis. Its major limitation is restenosis requiring repeated...

Mindfulness based approaches to tinnitus management: meditations on a new approach

Psychological approaches to tinnitus There is now widespread agreement that an individual’s interpretation of tinnitus can determine how distressing they find it. If tinnitus is regarded as non-threatening then habituation normally follows. If, however, tinnitus is interpreted as threatening, habituation...

JAMA Network Reader

Accessing content from The Journal of the American Medical Association (JAMA) and its nine specialty journals (including JAMA Otolaryngology – Head & Neck Surgery) has now become a bit easier, thanks to an app designed for viewing JAMA articles on...

Effects of diet and exercise on tinnitus

Subjective tinnitus is the perception of sound without any external stimulus. There is no consensus on the aetiology of tinnitus. Obesity is one condition that has been associated with subjective tinnitus. The authors conducted a randomised controlled trial to assess...

The hot nose

Capsaicin nasal spray can offer moderate to significant symptomatic relief to 70-80% of patients with idiopathic rhinitis (IR). Efficacy was also shown in lab studies. Nasal hyper reactivity (NHR), absence of allergy / infective rhinosinusitis, age limits (18-60), no anatomical...

Should we routinely perform steroid injections following microlaryngeal excision of benign lesions?

This retrospective cohort study assessed a single surgeon’s outcomes before and after the routine administration of intralesional triamcinolone following microsurgical removal of benign vocal fold lesions (polyps, nodules and cysts). A total of 211 patients were recruited for the study....