You searched for "chemotherapy"

251 results found

Which factors affect the postoperative CSF leak following endoscopic skull base surgery?

Endoscopic skull base surgery is being increasingly performed worldwide for skull base tumours. Common indications include pituitary tumours, rathke cleft cysts, chordomas, craniopharyngiomas and olfactory neuroblastomas. The most common and important complication following endoscopic skull base surgery is postoperative CSF...

An advance in imaging for sinonasal tumours?

Benign sinonasal growths are incredibly common, and malignant sinonasal growths thankfully rare. We know that malignant tumours often present late, and the imaging can sometimes be misleading, so the authors here compare using diffusion weighted imaging (DWI), dynamic contrast enhanced...

How do objective ratings of swallowing compare with patient-reported dysphagia QOL measures in the head and neck cancer population?

Swallowing may be assessed by a comprehensive battery of tools including instrumental/objective assessments, clinician-rated measures and patient-reported measures. The authors of this paper use secondary analysis to explore concordance between videofluoroscopy and a patient-reported dysphagia quality of life (QOL) measure....

Reducing the risk of Frey’s syndrome after parotidectomy – which methods are best?

Gustatory sweating or Frey’s syndrome is a well-recognised complication of parotid surgery. The reported incidence is highly variable, from 4% to 96%, with around 30% of patients reporting symptoms. A number of intraoperative techniques can be used to reduce the...

Long-term voice outcomes following transoral laser surgery versus radiotherapy for early laryngeal cancers

The oncological outcomes of transoral laser microsurgery (TOLM) for early laryngeal cancers are well-known to be very similar to radiation therapy (RT). The functional outcomes associated with each treatment modality are therefore of significant interest. This study is reported to...

Extracapsular dissection alone for low-grade malignancies of the parotid gland – oncologically sound?

The general treatment strategy advocated for a primary carcinoma of the parotid gland is surgical resection +/- adjuvant radiotherapy. A selective neck dissection is usually recommended in all cases of parotid malignancies, except for small, low-grade tumours. In this paper,...

How to improve olfaction and enhance quality of life after laryngectomy

Total laryngectomy diverts airflow away from the nose and, hence, olfaction is greatly impaired. Undoubtedly, this affects quality of life in terms of loss of taste and flavour. Surgery and devices to re-establish airflow into the nose can be difficult...

Suspect the unsuspecting in thyroid cancer

This article reminds readers of how often invasive thyroid disease can appear, as the symptomatology is minimal. Noticeable airway symptoms appear after 50% of the airway is involved and surgeons can often fall in the unsuspecting trap of discovering locally...

What is the evidence for contralateral tonsillectomy in TORS for known unilateral tonsil malignancy?

The concept of field changes by carcinogens within the upper aerodigestive tract is well established with reported rates of synchronous tumours of 4% and second primaries of 36%. The tonsil in particular has the highest rate of synchronous tumours, postulated...

Voice outcomes following extended laser resections for laryngeal cancer

It is now widely accepted that the oncological and voice outcomes following transoral laser microsurgery for early T1a glottic cancers are equivalent to, if not superior to, traditional radiotherapy. Voice outcomes following more extensive resections have not been as frequently...

Small vestibular schwannomas (VS) – is waiting the right thing to do?

VS management can be surgical, by radiosurgery or watchful waiting. Middle fossa approach (MCF) can be implemented in small and some medium-size tumours, and has the potential to preserve hearing. The authors measured quality of life of VS patients who...

Reconstruction of the Head and Neck: A Defect-Oriented Approach

This is the second Thieme book on head and neck cancer by this author that follows on from Head and Neck Cancer: an Evidence-Based Team Approach four years ago. It is a well-structured, up-to-date book in a readable layout with...