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Allergic rhinitis, the usual suspects
Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...
Allergen immunotherapy and allergic rhinitis – EAACI guideline 2017
Allergic rhinitis (AR) is a common chronic childhood disease with considerable social burden and impact on quality of life, frequently necessitating treatment with various combinations of antihistamines and corticosteroids. The allergen immunotherapy (AIT), sometimes known as desensitisation therapy, can modify...The Dilemma of Beethoven’s Deafness
Beethoven was one of the world’s greatest musicians, and his deafness is well known. Many details of his medical conditions are known, and various theories of his hearing loss have been proposed. Ludwig van Beethoven was born in 1770 in...In conversation with Erwin Offeciers
Professor Erwin Offeciers is a renowned adult and paediatric otologist, living and working in Antwerp, Belgium. He has extensive experience in cochlear implantation and has also spearheaded the well described bony obliteration technique. He is to sit on the forthcoming...Hearing screening during childhood using speech and sounds in noise
Although there is high prevalence of late-onset, progressive, and acquired hearing losses during childhood, these hearing losses can easily go undetected due to the lack of systematic hearing screening beyond newborn hearing screening. In this article, the authors share the...Hearing Care, cognitive decline and dementia: A public health challenge, or an opportunity for healthy ageing?
Brian Lamb, OBE and Sue Archbold PhD, Hon LLD A new document from The Ear Foundation, launched at European Association of Cochlear Implant Users (EURO-CIU) annual general meeting in Poland, reviews the latest evidence on the association between hearing loss,...
Bill Gibson: Pioneering Bionic Ear Surgeon
Professor Bill Gibson is one of the great pioneers of inner ear surgery and the recent publication of his biography is a reflection of his remarkable life and career. Bill Gibson: Pioneering Bionic Ear Surgeon will be enjoyed by everyone...
Do we need to intervene after complications of acute sinusitis in children?
omplications of acute sinusitis in children are not uncommon and some are managed surgically. The authors of this paper reviewed their experience of subsequent chronic rhinosinusitis (CRS). Nine of 86 patients required surgery in the 12 months after their initial...
Piezoelectric saw reducing sensory disturbance in mandibular osteotomies
This paper from Seattle in the United States looked at 20 patients with a mean age of 19.9 +/- 3.2 years with a fairly standard surgical movement. They found that functional sensory recovery of the inferior alveolar nerve resulted in...
What is in the Fountain of Youth?
Does the auditory system have to age? Can we become more like turtles or jellyfish and keep our internals running without degradation? This essay considers the theoretical underpinnings of biological processes in the cochlear, in particular the role of the...
