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Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?
Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...
Patient-reported outcome measures: what do the people say?
Patient-reported outcome measures (PROMs) assess and quantify health outcomes from the patient’s perspective. Defining these questionnaires as outcomes indicates that they are psychometrically sensitive to change. This article describes three PROMS: namely the Patient Reported Outcome Measurement Information System (PROMIS),...
Further understanding of GJB2 hearing loss
For many years, hearing loss has been an area which has attracted the interest of clinical and academic geneticists. Genetic testing for severe-profound hearing loss is now commonplace in many healthcare systems. Understanding the genetics of hearing loss has improved...
Laryngeal disorders associated with HIV infection
Following the introduction, and now widespread availability, of combined antiretroviral therapy, HIV has become a chronic disease with minimal or indeed no negative impact on life expectancy. As a result, there is a growing public health interest in establishing the...
Publishing - a predictor of an academic career in ENT?
Achieving a publication as a medical student renders ENT trainees six times more likely to publish again during postgraduate surgical training. But how does this correlate with subsequent subspecialty fellowship training and a career in academia? Johnson et al examined...
Robotic insertion of electrode array in cochlear implantation
Cochlear implants (CIs) are commonly used for profound bilateral hearing loss. They have specific national guidance for their insertion, however patients with a substantial residual acoustic hearing are potential CI candidates. Preservation of this residual hearing can be sought with...
Do personal listening devices cause cochlear synaptopathy?
Cochlear synaptopathy is a condition in which noise interrupts the synaptic communication between sensory inner hair cells and low spontaneous rate cochlear nerve fibres. Since these nerve fibres are associated with signal coding in noisy backgrounds, their disruption leads to...
Prognostic value of vascular ultrasonographic findings in patients with idiopathic sudden sensorineural hearing loss
Sudden sensorineural hearing loss is often idiopathic. Although the aetiology of idiopathic sudden sensorineural hearing loss (ISSNHL) is unclear, vascular compromise is one of the frequently proposed hypotheses to explain its pathophysiology. Existing studies have shown an association between ISSNHL...
Olfactory function and vitamin D
This Turkish prospective study evaluated olfactory function in individuals with primary vitamin D deficiency and the effect of replacement therapy on olfactory function over an eight-month period in 2019. A total of 91 individuals with vitamin D insufficiency were included,...
How common are swallowing problems in a general adult population?
This paper reports on the largest cross-continent study to date, looking at the prevalence of swallowing problems reported by adults in the community aged 18-65 years old. The authors used the Eating Assessment Tool (EAT-10) distributed via an online survey...
Algorithms to diagnose NIHL
Finding an efficient diagnostic tool for noise-induced hearing loss (NIHL) has been of research interest for a long time. There are several algorithms that compare expected age-related deterioration of hearing with the actual audiogram. This study aimed to compare a...
