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Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?
Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...
Argon plasma coagulation for epistaxis in HHT
In this study from the Czech Republic, the authors looked at the effectiveness of argon plasma coagulation (a non-contact form of monopolar electrocoagulation) in treating recurrent epistaxis in patients with hereditary haemorrhagic telangiectasia (HHT). The advantage of argon plasma coagulation...
Assessing the impact of e-cigarette smoke on the vocal fold
While the use of electronic-cigarettes (e-cigs) is increasing rapidly, little is known about the effects this has on the health of vocal fold. In this translational research study, authors compared the effects of e-cig vapour and cigarette smoke on an...
Recurrent facial palsy
Recurrent facial palsy is relatively rare, and its clinical features are not well known. The authors set out to investigate this further by undertaking a retrospective study of patients with recurrent facial palsy over a 14-year period. Only Bell’s palsy...
Active surveillance for papillary thyroid cancers – what is the risk of progression?
Papillary thyroid cancers (PTCs) are generally considered to be indolent malignancies with favourable outcomes. Active surveillance (AS) has consequently been trialled as a management option for small PTCs with no evidence of regional lymph node involvement, especially papillary thyroid microcarcinomas...
Intra orbital treatment to save the eye!
Invasive fungal sinusitis can be a devastating condition, and accepted management is surgical debridement of infected tissue, systemic antifungal treatment and reversal of immunosuppression. Orbital involvement is common, affecting up to 75% of cases, and in advanced disease orbital exenteration...
Hear me out – tiny steroid implants for fighting meningitis-induced deafness
Sensorineural hearing loss is the most common neurological complication of pneumococcal meningitis. Bacterial infiltration into the inner ear triggers inflammation, leading to cochlear fibrosis and sclerosis – damage that, in over a third of cases, affects both ears. Current Infectious...Supporting patients with chronic dizziness and investing in vestibular research
The Ménière’s Society is the UK’s leading vestibular charity. Their team is available to help patients access reliable information, source a vestibular specialist or talk to someone who understands what they’re going through.Early Egyptian medicine: nasal trauma and surgery in the Edwin Smith Papyrus
In ancient Egypt, with its towering pyramids and bustling cityscapes along the Nile, there existed a deep-rooted civilisation that excelled in more than the grandeur of monumental architecture. Frequent wars and battles shaped Egyptian society, not only defining its political...The death of Attila the Hun, a 70s film and Japanese cartoons
The 6th century Gothic monk, Jordanes, tells us that Attila the Hun, the notorious and allegedly merciless barbarian (who was a prime mover in the fall of the Roman Empire), died of a nosebleed on his wedding night in 453...
