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2386 results found

When to treat a fractured mandible?

This is a prospective study from Brisbane of 215 patients with a total of 359 fractures of the mandible. Nine outcome variables were analysed with a further 19 included to adjust for potential confounding. Treatment delay was found not to...

Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

Gamma Knife surgery for persistent or recurrent trigeminal neuralgia

Treatment of trigeminal neuralgia continues to be challenging. The treatment options include pharmacotherapy, or failing this, surgical options like microvascular decompression (MVD), radiofrequency ablation, pencil beam convolution and Gamma Knife surgery. The authors of this article have presented a series...

Shoulder function in patients undergoing neck dissection: its effects on work and leisure activities

Shoulder dysfunction is common after neck dissection and includes shoulder pain, limited abduction and scapular winging. Modifications of the radical neck dissection were designed to limit morbidity, however, even with accessory nerve-sparing neck dissections, shoulder dysfunction can be seen. Shoulder...

Endoscope assisted removal of jugular foramen schwannomas

This article, written by a renowned surgeon with extensive experience in removal of jugular foramen and skull base lesions, describes a new classification for jugular foramen schwannomas (JFS) and a template for selection of surgical approach for endoscope assisted removal....

Unanswered questions in adult ototoxicity associated with platinum-based chemotherapy

Do the potential side-effects on hearing and tinnitus need to be a ‘necessary evil’ of platinum-based chemotherapy? How strong is our evidence base when offering advice to patients and fellow clinicians? David Baguley and his team from the University of...

Neuromod publishes results of second large-scale clinical trial for tinnitus, shows greater improvement of symptoms

Neuromod Devices, the medical device company specialising in tinnitus, has published the results of its TENT-A2 (Treatment Evaluation of Neuromodulation for Tinnitus – Stage A2) clinical trial in the scientific journal, Nature – Scientific Reports in a paper titled ‘Different bimodal neuromodulation settings reduce tinnitus symptoms in a large randomized trial’.

Canal plugging for intractable Meniere’s disease

In this single centre retrospective study, the authors applied semicircular canal plugging, well known as a treatment for refractory BPPV, to intractable unilateral Meniere’s disease (MD) that had failed to respond to medical treatment with betahistine and hydrochlorothiazide. However, in...

Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...

Laryngopharyngeal reflux - would mucolytics help?

With laryngopharyngeal reflux (LPR) being such a common presenting complaint to ENT clinics, who would not want to have more, effective treatment options for patients suffering with this annoying condition? In their small randomised, controlled trial, Chae et al put...

How has management and outcomes of necrotising otitis externa changed over the past decade?

Necrotising otitis externa (NOE) remains a challenging condition for ENT departments, particularly with the increased prevalence of diabetes mellitus (DM) in the general population. There is no international consensus on treatment, although many institutions now have local guidelines drawn up...

A trial of house dust mite sublingual tablet in children with allergic rhinitis

The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...