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Biologic therapies for chronic rhinosinusitis with nasal polyps: a new paradigm

5 July 2022 | | ENT, Rhinology / Sinus
Surgery for nasal polyposis has evolved significantly in the last 30 years, and now the medical management may be on the cusp of a revolution. Biologics using monoclonal antibodies to target specific immune pathways have introduced a paradigm shift in...

Genetic testing in congenital hearing loss

7 January 2020 | | Audiology - Adult, Audiology - Diagnostic, Audiology - Paediatric, Otology | Genetics, Non-syndromic, Pediatrics, Sensorineural hearing loss
Advances in genetic testing over the last decade have reduced the cost and time such testing required and increased understanding of the genes involved in conditions like congenital hearing loss. This study from Atlanta looks at genetic testing from a...

Evolution of salivary gland pathology classifications

8 January 2024 | | Head and Neck, Rhinology / Sinus | Classification, Genetic alterations, Salivary gland cancers, Salivary gland pathologies, Salivary gland tumours
Targeted therapies for malignant salivary gland tumours have changed the treatment paradigm and therapy approaches. Better outcomes are now feasible. Choosing the treatment method requires a clear classification of the lesions. The authors of this paper reviewed the World Health...

Should intratympanic steroids be the first line treatment for sudden sensorineural hearing loss?

1 July 2017 | | Idiopathic sudden sensorineural hearing loss, intratympanic steroid treatment, meta-analysis, transtympanic steroid treatment
This article looked at whether intratympanic steroids (ITS) provide more benefits over systemic steroid therapy (SST) as initial therapy in patients with idiopathic sudden sensorineural hearing loss (ISSHL). This meta-analysis study, based on published RCTs, concluded that ITS treatment exhibited...

The integration of targeted therapy and surgery in advanced thyroid cancer clinical trials

3 November 2022 | | ENT, Head and Neck
One of the headline speakers, Mark Zafereo, will be talking at IFOS about thyroid cancer. We hear from his team about some of the areas they will be discussing. Locally advanced thyroid cancer generally refers to patients who have significant...
Clinical Otolaryngology journal cover image.

Treatment options for vestibular neuritis: systematic review and meta-analysis

2 March 2022 | | Neurotology, Otology | caloric tests, meta-analysis, recovery of function, steroids, vestibular neuritis
Vestibular neuritis (VN) is the third most common cause of peripheral vertigo. VN has been postulated to have viral aetiology and historically it was treated with steroids, until 2011 when a Cochrane review demonstrated lack of robust evidence behind this...

Hyposalivation: a review of current and future treatments

8 January 2024 | | ENT, Head and Neck
Hyposalivation remains a stubbornly difficult condition to treat, but novel therapies may not be far away. Saliva has many essential functions, including aiding digestion and swallowing, lubrication, maintaining tooth integrity and antibacterial activity. When patients experience reduced saliva production (hyposalivation),...

Save the date: WCA 2024

2 September 2022
The 36th World Congress of Audiology is taking place in Paris, 19–22 September 2024. The organisers have released a teaser video to encourage audiologists to attend a cutting-edge conference where diagnostic and therapeutic innovation, personalised medicine and translational research will...

Cochlear implantation in Tanzania: the journey and the outcomes

1 July 2021 | | Otology, ENT, Auditory Implants
It is estimated that over 400 million people worldwide live with disabling hearing loss, 39.9 million of whom live in sub-Saharan Africa [1]. This article by Dr Aveline Kahinga and Mr Ali Jaffer demonstrates the effort that has been made...

SEQaBOO: SEQuencing a Baby for an Optimal Outcome

1 July 2021 | | Audiology - Adult, Audiology - Diagnostic
There are at least 15 countries now running genome sequencing projects. The team in Manchester, UK, and Boston, USA, share their SEQaBOO project. Abstract SEQaBOO (SEQuencing a Baby for an Optimal Outcome) will transform newborn hearing screening (NBHS) by bringing...

Drawing pictures and telling stories: treating tinnitus in childhood

24 May 2017 | | Audiology - Paediatric, Tinnitus
There is increasing awareness that tinnitus is not restricted to adults. Indeed, the available evidence suggests that some experience of tinnitus in children is fairly common [1]. For many, tinnitus has little effect and requires limited or no intervention. For...

Dysphagia in complex laryngology – maintaining the balance

4 May 2023 | | ENT, Laryngology / Swallowing / Voice, Speech and Language Therapy
These authors from the speech and language therapy department at Imperial College Healthcare NHS Trust, describe their view of a patient-centred approach to managing dysphagia in complex laryngology. Careful consideration of the balance of airway, voice and swallow, which is...