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922 results found

Outpatient solution for a Patulous tube?

Definitive diagnosis and management of Patulous Eustachian tube (PET) is unsatisfactory. Several different treatment methods are currently used for PET which itself indicates no satisfactory solution. The objective of this study was to compare the outcomes of two different treatment...

Benign positional paroxysmal vertigo manoeuvres in children and adolescents: a systematic review

In this paper of Saniasiaya et al, the literature review is conducted in accordance to the PRISMA consensus, aiming to investigate the outcomes of canalith repositioning manoeuvres (CRM) to treat benign paroxysmal positional vertigo (BPPV) in a paediatric and young...

The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...

Do adhesions actually cause nasal blockage?

All of us who perform nasal surgery are familiar with the disappointing presence of nasal adhesions (NA) or synechiae in our postop patients. These can often lead to patients deriving less perceived benefit from their surgery than that which they...

Application of balloon dilatation in chronic eustachian tube dysfunction

Chronic eustachian tube dysfunction prevails in 1% of the adult population and can predispose to middle ear disease. There are subjective and objective features of this condition that can affect quality of life. The common methods to treat eustachian tube...

Are vascular loops at the CPA of any clinical significance?

Neurotologists have grappled with this question for many years. The aim of the study was to determine the clinical relationship of vertigo symptoms with vascular loop compression syndrome using 3D T2WI turbo spin echo high-resolution MRI. The study included 417...

Objective testing for Eustachian tube dysfunction

Eustachian tube dysfunction (ETD) is typically diagnosed based on subjective symptoms and examination leading to wide variation in its diagnosis and management. The search for an objective test has looked at ways of measuring the passage of air through the...

Does endoscopic stapling for pharyngeal pouch supersede open repair?

Endoscopic stapling for pharyngeal pouch is generally considered to be less invasive, safe and with fewer complications, resulting in quicker recovery and a shorter hospital stay. Whether these factors hold in the long-term follow-up is the subject of this interesting...

Role of intranasal steroids after radiotherapy for nasopharyngeal carcinoma

Rhinosinusitis often follows radiotherapy in the treatment of carcinoma of the nasopharynx. The interval and severity may vary with the dose of radiation and stage of the carcinoma. In this randomised, controlled study, patients who developed rhinosinusitis after radiotherapy treatment...

Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

Active intervention in small schwannomas associated with higher incidence of long-term hearing loss

This article represents collaborative data of hearing outcomes from tertiary centres in Norway and the United States. They studied data of patients with less than or equal to 3cm vestibular schwannoma who underwent observation, primary microsurgery and Gamma Knife surgery...

Which is worse – unilateral or bilateral tinnitus?

Few studies have analysed subjective aspects of tinnitus or the association between clinical characteristics and the directionality of tinnitus. The study subjects comprised 207 patients who presented with tinnitus over two years and underwent tinnitus-related physical examinations and tinnitograms (includes...