You searched for "genomics"

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Molecular and genetic nature of skull base tumours drives management

This article reviews the molecular basis and paradigm shift in the diagnosis and management of skull base tumours. It is now known that the phenotype of meningiomas is influenced by their genotype. Endolymphatic sac tumours are observed in up to...

Evolution of salivary gland pathology classifications

Targeted therapies for malignant salivary gland tumours have changed the treatment paradigm and therapy approaches. Better outcomes are now feasible. Choosing the treatment method requires a clear classification of the lesions. The authors of this paper reviewed the World Health...

4th Annual Inner Ear Disorders Therapeutics Summit

2024 has been an important year with recent back-to-back positive results for gene therapy for rare genetic hearing disorders and major headways in otoprotective, restorative and regenerative small molecules and cell therapies for acquired hearing loss. The Inner Ear Disorders...

Blogs

Blogs continue to be an excellent medium for sharing ideas and information with the public simply and effectively. With more than 150 million blogs currently circulating the Web, there is no shortage of high quality blogs related to the field...

My experience of addiction

In this incredibly honest and thought-provoking article, we hear from an anonymous doctor who has struggled with addiction. The nature of addiction is a subject of interest to a broad range of scientific disciplines, from medicine to psychology, psychotherapy and...

An idiot’s guide to the Ministry of Health

Neville Chamberlain on an ill-judged charm offensive. Now I like to consider myself a well brought up sort of chap, and was always taught never to bring up religion, politics or (heaven forfend!) a lady’s name at the dinner table....

Lies, damned lies and relative risk reduction

Chris Potter has a thing or two to say about the use of statistics and, in doing so, he takes us to a Friday night steak house that is prone to airway disasters and on a short tour of his...

The workplace environment and doctors’ health (ENT)

It is well established that doctors have higher levels of stress, depression and suicide than the general population [1] and most other professional groups (Figure 1 illustrates the factors that can make us ill). In addition they have high levels...

Measuring client-centred outcomes in audiology: towards a parsimonious solution

From an international driver to the client-centred care model; in this article Anthony Hogan explores outcome measures for individual goal setting and measuring those outcomes. Introduction When people present for hearing help, they are typically looking for solutions to the...

The use of THRIVE in laryngology and phonosurgery

The team in Lewisham has been using THRIVE for our phonosurgical cases for about a year. Here, we discuss the pros, cons and potential pitfalls of setting up and using THRIVE as ventilation during anaesthesia rather than using an ML...

AUDIOLOGY - In conversation with Hans Henrik Philipsen

So your background is in social research, how did you develop an interest in this area? I have always had an immense curiosity when it comes to understanding other people and other cultures. My early experience as a teenager in...

Hearing loss in the young and self-esteem

How can those involved in the care of children with hearing loss identify those at risk of low self-esteem? This study provides some guidance. Overall differences from hearing peers in terms of communication skills, physical appearance and social maturity place...