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Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody
Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...
Does minimally invasive surgery under local anaesthesia have a role in the management of chronic rhinusinusitis?
A formal FESS procedure usually done under local anaesthesia is considered as gold standard in the management of chronic rhinusinusitis. However, success is hampered by a significant recurrence rate of polyps requiring revision surgery, long waiting lists, reluctance of elderly...
Daflon – a new way to treat idiopathic epistaxis
Epistaxis is a common ENT emergency and most cases are idiopathic. Flavonoids are natural substances with variable phenolic structures that are found in fruit and vegetables and take effect on blood vessels. Daflon is proposed to control epistaxis by “improving...
Cycle helmets protective against facial injuries?
This is a meta-analysis completed by a maxillofacial unit on the South Coast of England. Nine studies from an initial literature review of 102 were included in the analysis. Cycling has been reported as the cause of 3-20% of facial...
DIY Epley manoeuvre
This is an interesting paper that looks at getting patients to do their own particle repositioning manoeuvre (PRM) after having it done by a clinician (‘Epley’ to you and me although there are some slight differences) once a week for...
Painful temporomandibular joints
This paper is a meta-analysis of randomised controlled trials comparing arthrocentesis with conservative management in painful and restricted mouth opening temporomandibular joint symptoms. Temporomandibular joint dysfunction comprises a spectrum of disorders commonly involving facial pain and loss of oral function...
Obstructive sleep apnoea: Does maxillomandibular advancement work?
This is a paper from the Netherlands reviewing 62 patients who underwent maxillomandibular advancement for moderate to severe obstructive sleep apnoea. The authors observed a 71% success rate with mean apnoea hypopnea index (AHI) reduction of 69%. There was no...
Surgery for snoring
The prevalence of sleep-disordered breathing is rapidly increasing. There is variable evidence for surgical treatments for snoring currently. This Belgian study was a retrospective review of 84 patients who underwent surgery for snoring between May 2011 and December 2015. A...
Microbiome changes after endoscopic sinus surgery: all is not what it seems
As we keep fighting a losing battle with bacteria and antibiotics, it becomes clear that it is not about killing bacteria, not even diminishing the bacterial load, but rather about shifting the different types of bacteria that colonise and live...
SpeechEasy® for stuttering
In this article, the authors describe their experiences with an altered auditory feedback (AAF) device: SpeechEasy® during a random clinical trial. AAF has been reported in other laboratory studies to reduce stuttering events without influencing the rate, intensity or frequency...
FESS for recurrent acute rhinosinusitis: at last, some data
As noted in both the EPOS 2012 and in the (more recent) ICARS 2016, there is a paucity of evidence on the effectiveness of surgery for recurrent acute rhinosinusitis (RARS). The authors used a control group of patients with CRSsNP,...
