You searched for "trial"

1326 results found

Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry

We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...

INTEGRATE: Uniting collaborative research in ENT

Exposure to clinical research as a trainee is often sporadic and unstructured, despite it featuring in both the GMC’s Good Medical Practice and the ISCP’s syllabus for all surgical specialities, including otolaryngology [1,2]. The majority of trainees undertake small-scale research...

Virtual reality simulation training for cochlear implant surgery

Temporal bone virtual reality (VR) simulation training has been shown to be a useful tool for learning mastoidectomy. The authors aimed to evaluate the role of VR in cochlear implant (CI) surgery. The study was performed as part of a...

Long-term curative effects of microvascular decompression for hemifacial spasm

This article describes results of a multicentre prospective trial performed to evaluate long- and short-term outcomes and complications of patients who underwent microvascular decompression (MVD) for hemifacial spasm (HFS). The surgeries were performed by surgeons with more than 15 years...

Surgery for snoring

The prevalence of sleep-disordered breathing is rapidly increasing. There is variable evidence for surgical treatments for snoring currently. This Belgian study was a retrospective review of 84 patients who underwent surgery for snoring between May 2011 and December 2015. A...

Septal surgery made easy?

The injecting of the greater palatine canal has been documented for some time. The authors in this paper expand this to the more common procedure of the septoplasty. They summarise the pros and cons published regarding the technique in sinus...

Quality of life after FESS or balloon sinuplasty

This randomised control trial compared the SNOT-22 questionnaires both pre-operatively and three months post-operatively in patients with chronic rhinosinusitis undergoing either FESS or balloon sinuplasty to the maxillary sinus. Forty two patients participated in the study, 21 in each treatment...

Endolymphatic sac surgery for Ménière’s disease

This is a very useful meta-analysis for those that perform surgery for Ménière’s disease. It specifically looked at differences in various forms of endolymphatic sac surgery (ESS). A total of 36 papers were included. The results: ESS controls vertigo in...

In conversation with Professor Jos Eggermont

Having known Jos for many years, I jumped at the opportunity to catch up with him for our Nov/Dec 2020 series of tinnitus items. My questions reached him during lockdown, and he was enjoying the chance to get on top...

Cell therapies for hearing loss

Cell therapies could offer a way to repair damage to the auditory system and reverse many types of hearing loss. This article looks at the progress being made.

Vascularised tissue in salvage total laryngectomy

Chemoradiation (CRT) has become the mainstay for locally advanced laryngeal cancer since the RTOG 91-11 trial. Unfortunately there is still a substantial demand for salvage laryngectomies, which have a higher complication rate, the most notable being pharyngocutaneous fistula (PCF). Several...

Intratympanic steroids in Ménière's disease: what’s the evidence?

The days of drastic surgery for Ménière's disease are long gone. We know that intratympanic injections can deliver high doses of medication to the inner ear with minimal discomfort and minimal risk. But how do we choose from the myriad...