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Difficult consultations with HPV-positive oropharnyeal cancer patients

The aetiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is well established, and its incidence has massively increased over the last decade, whilst the incidence of HPV-negative OPSCC is declining. Although we know that HPV-positive OPSCC...

The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

Laryngeal papillomatosis

Laryngeal papillomatosis remains one of the most frustrating conditions seen by laryngologists. Sam Majumdar gives us an overview of the current science and clinical practice. Human papilloma virus is a small (> 8kb) double stranded DNA virus with approximately 200...

Transnasal oesophagoscopy (TNO) and balloon dilatation under a local anaesthesia

Many of us are becoming more and more familiar with the use of transnasal oesophagoscopy. It has a number of well-described uses in the outpatient setting and is well tolerated by our patients. Yakubu Karagama describes taking this technique a...

The effects of leisure noise exposure on young people’s hearing

There is growing concern regarding the effects of leisure noise exposure on young people’s auditory system. Information provided by healthcare professionals should be evidence-based; Hannah Keppler discusses some recent findings about hearing in young people. Excessive noise exposure can lead...

The evolving role of OAEs in newborn hearing screening

An admission on emissions from James Hall! OAEs hold an established place in the screening of infants; Professor Hall introduces how OAEs established this position and the advances keeping the test relevant to today’s infant screening battery. Introduction Truthfully, when...

Otoacoustic emissions in the diagnostic test battery for hearing loss

So, they are great for screening, but how can otoacoustic emissions be integrated into the diagnostic test battery? Beth Prieve examines the role of diagnostic OAEs by asking three simple questions. Audiologists and otolaryngologists are familiar with otoacoustic emissions (OAEs)...

Vocal fold motion impairment following intubation – how likely is it to recover?

Ed’s Choice reviews a timely paper investigating prolonged intubation on vocal fold motion. The current scientific literature is dominated by studies examining COVID-19 and its widespread effects on health and healthcare delivery but will be old news by the time...

Taking a fresh look at otoacoustic emissions

So what has changed in four decades of OAEs? Do we now have all the answers? Have we reached our optimum recording ability? Professor Kemp explains what we know, what we don’t know and what’s to come. In the 40...

Imaging in hyperparathyroidism

Following their caudal migration at eight weeks of development, the parathyroid glands normally locate posterolaterally to the upper pole of the thyroid gland at the level of the cricoid cartilage (superior parathyroid glands arising from the fourth branchial pouch and...

First UK hypoglossal nerve stimulation implant in the treatment for moderate to severe OSA

Obstructive sleep apnoea has been treated in many different ways over the years. We hear from Yakubu Karagama about one of the latest surgical developments. Introduction Obstructive sleep apnoea (OSA) is by far the most common sleep disorder, affecting all...

“Oh Manchester is Wonderful”...And other chants you might hear from the football stands or at BACO

Chris Potter is a lad of the North West, and we see him here letting his bleach blond hair grow out to show us his Northern roots. When I was a lad, Manchester was a troubled city in apparent terminal...