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eNOS and OME

The pathophysiology of otitis media with effusion (OME) is multifaceted. The authors tackled the nitrous oxide (NO) and platelet activating factor (PAF) pathways and the genetic polymorphism of endothelial nitrous oxide synthetase (eNOS). DNA analysis by PCR and restriction fragment...

Recalcitrant chronic rhinosinusitis: What to do next?

Whilst the majority of patients with chronic rhinosinusitis (CRS) will significantly improve with treatment, we are sometimes left with a ‘hard-core’ of nasal cripples who fail to improve despite our best efforts. How can we deal with these patients? Valerie...

Unexplained dizziness in elderly patients

How do we explain unexplained dizziness in elderly patients? How far should we go with investigations? And most importantly, how should we manage this challenging and expanding group of patients whose balance affects their safety? Richard Ibitoye and Diego Kaski...

Do we need contrast MRI when screening for vestibular schwannoma?

Gadolinium contrast enhanced T1-weighted (gT1w) MRI images of the internal acoustic meati have long been considered the gold standard in the diagnosis of vestibular schwannoma (VS). However, the addition of contrast to the MRI examination increases the cost and time...

Taking a fresh look at otoacoustic emissions

So what has changed in four decades of OAEs? Do we now have all the answers? Have we reached our optimum recording ability? Professor Kemp explains what we know, what we don’t know and what’s to come. In the 40...

JLO surgical video: right selective neck dissection levels 2-5

Surgical training has become more challenging following the introduction of the European Working Time Directive. The consequences of reducing the amount of time we operate has driven us to look for other resources to fill this gap. These initially began...

Aided speech auditory brainstem response

Auditory brainstem response (ABR) is commonly used for hearing screening and is considered as one of the important means of objective audiometry. Speech ABR is a relatively new concept and is regarded as a marker of speech encoding at the...

Back to the future: aphasia therapy post stroke

When speech and language therapist first started working with people with stroke-related aphasia, they employed a general stimulation approach, the same with every patient they met. In the '70s this changed, and a more tailored approach was developed whereby therapists...

Guillotines from Joseph‑Ignace Guillotin to Greenfield Sluder

Joseph‑Ignace Guillotin. The politician and physician Joseph-Ignace Guillotin (1738-1814) was so disgusted by brutal head and shoulder injuries sustained in ‘failed attempts’ by drunken axe-wielding executioners during the French Revolution that he and surgeon Antoine Louis (1723-1792) advocated not only...

Temporoparietal fascia flap for blind sac closure

Chronic ear disease can be challenging to manage and difficult for patients to live with. In this article, the authors describe their technique for otomastoid obliteration and blind sac closure of the external canal allowing for a more tolerable situation...

On-call in ENT Surgery

The On-call in ENT Surgery, as part of the On-call Series, is written explicitly as the “survival guide” for all junior doctors starting out in ENT or as “a tool to aid consolidation of knowledge gathered by more senior ENT...

What blood tests should be requested to investigate vocal cord paralysis?

Patients who are discovered to have a vocal cord palsy with no obvious cause on history or examination routinely undergo investigations to exclude an underlying pathology. Cross-sectional imaging of the relevant recurrent laryngeal nerve is required, but considerable variability has...