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Biologic therapies for chronic rhinosinusitis with nasal polyps: a new paradigm
Surgery for nasal polyposis has evolved significantly in the last 30 years, and now the medical management may be on the cusp of a revolution. Biologics using monoclonal antibodies to target specific immune pathways have introduced a paradigm shift in...Targeting the microbiome in chronic rhinosinusitis
Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...Rehabilitation of single-sided deafness with cochlear implants
The relatively recent emergence of cochlear implantation as a potential means of restoring hearing to a deafened ear, in the presence of normal hearing in the other ear, has proved an exciting and yet surprising development. James Tysome explores the...The astronomer’s nose: Tycho Brahe’s controversial prosthesis
Tycho Brahe (1546-1601) is a familiar and colourful figure in the history of science. The immense quantity of data he collected during his lifetime would enable the work of Johannes Kepler and has gained him admission to the astronomical pantheon....Pinnaplasty for prominent ears
Pinnaplasty is a challenging yet rewarding procedure for which many different techniques have been described. In this article the authors describe their favoured technique, including the important postoperative care. Prominent ears can be a source of significant psychological distress in...The ear-brain connection in cochlear implant users: learning to listen again
While the cochlear implant (CI) has been a tremendous success in restoring hearing to deaf individuals, the implantation outcome still varies across CI users [1]. Some demographic factors, such as duration of deafness, and peripheral factors, such as electrode placement,...Electronic nicotine delivery systems (e-cigarettes): what you need to know
As an aid to stopping smoking e-cigarettes may have a role, but they are heavily promoted by industry as a leisure pursuit and desirable fashion accessory. Sneh Biyani and Craig Derkay gives a thorough account of what we know about...
