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Endotypes in chronic rhinosinusitis: clinical relevance
Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...Giacomo Puccini’s laryngeal cancer
Giacomo Puccini, one of the best known composers of all time, was diagnosed with laryngeal cancer and died from the disease in 1924. In this article, Rosario Marchese-Ragona and Alessandro Martini describe Puccini’s experience of the disease with quotes from...Harnessing head and neck cancer genomics for personalised medicine
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...VACANCY: Band 7 Audiology Lead (Deputy Manager), Belfast
The following job opportunity is now available.From the editor JanFeb 2022
The start of a new year is always an opportunity to look forward with a renewed sense of hope and optimism. It is also a chance to look back at the previous 12 months and, looking back to early 2021, we were just at the dawn of the COVID vaccination programme – this had developed at an unprecedented pace, and gave us all huge cause for excitement and hope.Genetic discovery using animal models: presbyacusis
By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...
Basic Fundamentals in Hearing Science
The preface to this textbook explains that its inspiration came from an identified need to replace a previously discontinued hearing science textbook authored by Durrant and Lovrinic in 1995. This was an excellent resource that I used throughout my own...
