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People with language-led dementia in India

Primary Progressive Aphasia (PPA) is a language led dementia characterised by slowly worsening speech and language. It is associated with atrophy of the dominant temporal-parietal lobe regions and is commonly caused by frontotemporal or Alzheimer’s pathologies. There are three PPA...

Patient-reported outcome measures: what do the people say?

Patient-reported outcome measures (PROMs) assess and quantify health outcomes from the patient’s perspective. Defining these questionnaires as outcomes indicates that they are psychometrically sensitive to change. This article describes three PROMS: namely the Patient Reported Outcome Measurement Information System (PROMIS),...

Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

Globus, reflux or perhaps both?

We rarely do an ENT clinic without encountering a patient with persistent or recurring feeling of a lump or foreign body in the throat. We are also familiar with patients dreading to hear the C word after the endoscopic examination...

BPPV and pregnancy

This narrative review explores the limited evidence surrounding benign paroxysmal positional vertigo (BPPV) during pregnancy. Although BPPV is the most common vestibular disorder and is known to affect women more frequently than men, the literature specifically examining its occurrence in...