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Long-term results of injection laryngoplasty with polydimethylsiloxane (Vox) for unilateral vocal fold paralysis

Polydimethylsiloxane (PDMS) is widely used for vocal cord injections to treat patients with a vocal cord palsy. It is commercially available as the Vox implant system. Alternative compounds that can be employed include hyaluronic acid and calcium hydroxyapatite (Radiesse Voice)....

Reactive lesions of the contralateral vocal cord – excise or leave?

It is well recognised that benign lesions of one vocal cord can give rise to reactive lesions of the contralateral vocal cord directly opposite to the primary lesion. These contralateral reactive lesions (CRLs) are thought to arise due to impact...

Surgical voice restoration after laryngopharyngectomy

Voice restoration is one of the key rehabilitative steps after laryngectomy or total laryngopharyngectomy (TLP). Patients who undergo TLP require reconstruction – increasingly commonly with microvascular free flaps. Despite their advantages in terms of fistula rates and swallowing outcomes, these...

The laryngeal microdebrider – a useful adjunct in the surgical treatment of Reinke’s oedema?

The surgical treatment of Reinke’s oedema traditionally involves a cold steel incision placed in the lateral aspect of the vocal fold with aspiration of the characteristic gelatinous contents. In this paper, the authors compare voice outcomes in patients treated with...

What are the airway, voice and swallowing outcomes of a mucosal-sparing surgical approach to improving the glottic airway in bilateral vocal fold immobility?

Bilateral vocal fold immobility (BVFI) causes significant breathing problems as well as voice and swallowing difficulties. Surgical interventions aim to enlarge the glottic outlet by altering or removing glottic structures which improve breathing but often lead to worsening dysphonia and...

Wound moisture sensing in traumatic wounds

Wounds can be small and unpleasant, or may be large and life-threatening. The skin is a physical and an immunological barrier to infection, and any defect in the integrity of the skin may enable bacterial or fungal invasion. The successful...

Pre-clinical development of magnetic delivery of therapy to middle and inner ears

Why are we developing this technology? A key problem in drug delivery is getting the therapy to the right place in the body, which is especially challenging for targets that are small, deep and are protected or surrounded by anatomical...

When dinosaurs ruled the earth

Optimism is abundant in medical research, but frequently ends up being tempered with reality. In his inimitable style, Chris Potter looks back over his career – starting with his medical school memories of Bentley-driving ENT consultants, and moving forward through...

Dizziness in OSA patients– is there a link and can CPAP treat it?

This is a small study which proposes an interesting hypothesis - that in patients with both dizziness and OSA, treatment of their sleep disorder can provide resolution of their dizziness symptoms, which were otherwise refractory to standard treatment, particularly in...

New treatment for chronic voice disorders

A new regenerative treatment for people with chronic voice disorders has been used in the UK for the first time. Guy’s and St Thomas’ is the first NHS trust in the country to provide this treatment in the larynx (or voice box) for patients with chronic voice conditions that cause voice change or dysphonia, making the voice sound hoarse, strained, breathy, weak, or fluctuate in pitch and loudness.

Standardising videofluoroscopy assessment for bottle-fed babies

Swallowing problems in babies may occur for many reasons including complex medical problems, premature birth, and low birth-weight. Dysphagia causes several further morbidities such as poor nutrition and compromised respiration, often raising distress for both infants and their caregivers. Early...

Cystic fibrosis – sinus surgery delays chronic Gram-negative lung infection

This prospective clinical follow-up study is of 106 patients with cystic fibrosis in Copenhagen. Morbidity and mortality in CF are significantly associated with pulmonary colonisation and infection, usually with Gram-negative bacteria. Initially this can be well treated with antibiotics until...