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An algorithm to distinguish between distant metastases and metachronous lung primary in patients with HPV-related oropharyngeal cancer

Distinguishing between distant metastases of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) and metachronous primary lung squamous cell carcinoma (SCC) is important as it has implications for treatment, prognosis counselling, and registry data. Although p16 immunohistochemistry (p16 IHC) is widely accepted...

The stigma of HPV in oral cancer

The increase of oropharyngeal carcinoma (OPC) in the developed world seems to be largely caused by infection with the human papillomavirus (HPV). HPV is a group of 150 DNA viruses that are common and most people will be infected at...

The Laryngeal Pacemaker – developing an innovative solution for bilateral vocal fold paralysis

Bilateral vocal fold paralysis is a difficult condition to manage, with surgical interventions previously limited to tracheostomy or arytenoidectomy. Re-innervation surgery has been developed and, in recent years, a Laryngeal Pacemaker is now in clinical trials. We speak to two...

The Laryngeal Pacemaker – developing an innovative solution for bilateral vocal fold paralysis

Bilateral vocal fold paralysis is a difficult condition to manage, with surgical interventions previously limited to tracheostomy or arytenoidectomy. Re-innervation surgery has been developed and, in recent years, a Laryngeal Pacemaker is now in clinical trials. We speak to two...

A medical student’s perspective on the future of obstructive sleep apnoea management

Obstructive sleep apnoea remains an immensely challenging condition to treat. Many treatments have been used over the years, but no single management strategy has proven significantly better than the others. We hear about some technological innovations in the field of...

Guidelines on COVID-19 published by Asia Pacific Laryngology Association (APLA)

Due to a vast geographical spread with diverse socio-economic conditions in the Asia Pacific countries, APLA Founding Chair, Vasant Oswal, President, David Lau, and Secretary, Vyas Prasad decided to publish guidelines on COVID-19 in the form of an ‘International Consensus',...

Laryngeal evaluation during COVID-19 using transcervical ultrasonography

In light of the COVID-19 pandemic, the authors highlight their protocol of transcutaneous laryngeal ultrasonography as an alternative to flexible fibreoptic laryngoscopy when appropriate. This is to reduce the risk of aerosolisation posed by laryngoscopy. Ultrasonography is a rapid, non-invasive...

Dysplasia at the margins of laryngeal cancer specimens following laser resection – is conservative management appropriate?

Transoral laser microsurgery (TOLM) remains the cornerstone of treatment for early laryngeal squamous cell carcinomas. Whilst the hope is always to achieve a complete surgical excision with clear margins, it is sometimes the case that on histological analysis, disease is...

What factors lead to poor outcomes for children with acute post-intubation laryngeal injuries?

Endotracheal intubation is well known to carry a risk of acute laryngeal injury. These problems range in severity and can lead to chronic problems but, when laryngeal injuries are identified and treated early, there are fewer complications. The authors of...

The pioneers of endoscopy and the sword swallowers

Adolf Kussmaul drew inspiration from an unlikely source to further the development of endoscopy… The early pioneers of airway endoscopy and oesophagoscopy were bedevilled by two major and seemingly insurmountable problems. One was the paucity of light sources, with reliance...

In conversation with Dr Peter Belafsky

Dr Peter Belafsky. Peter – tell us about your background I was born in Philadelphia and went on to study at Vassar College which is a small liberal arts school in upstate New York. I then attended Medical School in...

Upper airway endoscopy: achieving a balanced service whilst minimising the conflict of sustainability

Nasal endoscopes present a unique challenge in balancing sustainability and practicality. Both disposable and reusable scopes may have distinct roles in modern practice. Flexible endoscopy of the upper aerodigestive tract is an essential technique that facilitates detailed assessment of the...