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Endotypes in chronic rhinosinusitis: clinical relevance

Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...

Circular economy approach to reducing your carbon footprint in your ENT operating room

Although our operating rooms consume significant resources, some simple changes can have considerable impact in reducing greenhouse gas emissions. Here are 10 such simple things we can do. Waste is one of the largest contributors to a hospital’s carbon footprint,...

Hyperacusis and autism spectrum disorder

Several different auditory deficits have been found to be co-morbidities of ASD. This article reviews literature with respect to the relationship between hyperacusis and ASD. Autism spectrum disorder (ASD) can be characterised as a neurodevelopmental condition that is marked by...

Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...

The sound of music for adult cochlear implant recipients

Dr Valerie Looi has dedicated her academic career to investigating music perception in people who have cochlear implants, and more recently, the potential of music training for improving their music perception. This article outlines current research relating to music perception...

How good ideas become great products: in conversation with three medical innovators

Ever had a great idea for an innovation that would significantly improve your practice, but wondered how to go about developing it? Lucy Dalton interviewed three consultant ENT surgeons-come-successful innovators (one international, one novice and one experienced) who explain what...

Pre-clinical development of magnetic delivery of therapy to middle and inner ears

Why are we developing this technology? A key problem in drug delivery is getting the therapy to the right place in the body, which is especially challenging for targets that are small, deep and are protected or surrounded by anatomical...

Imaging in hyperparathyroidism

Following their caudal migration at eight weeks of development, the parathyroid glands normally locate posterolaterally to the upper pole of the thyroid gland at the level of the cricoid cartilage (superior parathyroid glands arising from the fourth branchial pouch and...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

In memory of Robert Allan Yorston (10th March 1920 – 1st October 2016)

In this special feature article, Alan Gibb writes a touching tribute to his friend and colleague Dr Bob Yorston, a Dundee otolaryngologist, who had a special talent for humour and art. In addition to illustrating the eighth, ninth and tenth...

Near-miss in otolaryngology head and neck surgery

It is recommended by John Fenton that we as a specialty need to embrace the concept of, take responsibility for and learn from all near-miss events, rather than our traditional haphazard approach of an occasional educational anecdote or case report....