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The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

Patient and public involvement in research

One step further from involving patients in setting research priorities is to involve them in the planning and recruitment stages of the subsequent trials and studies. Here, Carl Philpott and Aneeka Degun explain the concept of Patient and Public Involvement...

Staphylococcus aureus as a cause of refractory chronic rhinosinusitis

Staphylococcus aureus has long been linked to chronic rhinosinusitis, particularly recalcitrant cases. In this article, Alkis Psaltis describes how newer techniques have shown higher rates of S. aureus infection than were previously thought, and explains how the bacteria are able...

Exploring teenagers’ access and use of assistive hearing technology

Children require good signal-to-noise ratios for optimum listening and learning. The use of remote microphone technology can be of benefit, yet older children often resist using it. Jennifer Groth reviews the challenges facing older children in the use of remote...

Are ENT patients who research their symptoms online better informed?

All our patients look up their symptoms online before they visit us, don’t they? And patients who do so are better informed than those who don’t, right? Well, that’s not actually the case… The ‘information era’ More information is now...

Can we prevent chronic rhinosinusitis?

The old adage ‘prevention is better than cure’ is considered by Professor Hopkins in respect to chronic rhinosinusitis, a condition affecting around 10% of the adult population and associated with huge impact on quality of life and economic cost. A...

Laryngeal papillomatosis

Laryngeal papillomatosis remains one of the most frustrating conditions seen by laryngologists. Sam Majumdar gives us an overview of the current science and clinical practice. Human papilloma virus is a small (> 8kb) double stranded DNA virus with approximately 200...

When things go wrong

The new-age, Paediatric Surgeon, Ray Clarke, (fear uasal, íseal), eloquently demands throwing off the shackles of the past and welcomes the dawning of an era of openness, transparency and candour, preferably suffused with compassion for both the patient and the...

An overview of human factors in ENT and anaesthesia

James Bates and Chris Frerk are both passionate about how human factors science can improve safety in healthcare and have co-authored this article describing how communication, ergonomics and other non-technical skills are making operating theatres safer. There is no doubt...

Barrier and opportunities for hearing care: finding a way forward for all

Ideal models of care for communities can include tailored ear and hearing care interventions. Barriers exist at an individual and societal level to realise the vision of hearing care for all, regardless of country or resource setting. Affordability of hearing...

Taking life by the throat

Patients suffering with problems with their voice, airway and/or swallowing can find their symptoms immensely distressing, and their care places a huge burden on healthcare systems. We hear from a world-leading laryngologist on current and future directions. Field of interest...

Olfaction in CRS

Conventional teaching tells us that hyposmia in chronic rhinosinusitis is due to mechanical obstruction of the olfactory cleft. But it might be that the story is slightly more complicated than that. Olfactory dysfunction is a common feature of chronic rhinosinusitis...