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OTO-104 in noise-induced and cisplatin-induced hearing loss
These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...Promoting human rights of deaf communities in low-resource settings
Stigma and misconceptions about deafness are serious impediments for many deaf people to realise rights and potential in some of the most challenging situations globally. Around 430 million people are estimated to live with moderate or higher levels of hearing...Promoting human rights of deaf communities in low-resource settings
Stigma and misconceptions about deafness are serious impediments for many deaf people to realise rights and potential in some of the most challenging situations globally. Around 430 million people are estimated to live with moderate or higher levels of hearing...
Lower respiratory involvement in allergic rhinitis and chronic sinusitis
The recent ARIA (Allergic Rhinitis and its Impact on Asthma) project has generated interest in simultaneous involvement of the lower respiratory airway in cases of chronic rhinosinusitis and allergic rhinitis. This study takes into account the extent of pulmonary function...
Management of frontal sinus fractures
Frontal sinus fractures are uncommon (associated with around 5-15% of facial fractures). The authors divide frontal sinus fractures into isolated anterior table fractures, fractures involving the frontal sinus outflow tract and posterior table fractures, discuss some of the recent relevant...
A multidisciplinary approach to the management of frontal sinus fracture
Frontal sinus fractures account for about 5% of all facial trauma. Fractures of the posterior wall may result in cerebrospinal fluid (CSF) leak and meningitis, while obstruction of the outflow tract can cause sinusitis and mucocele formation. However, there are...
