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IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Globus, reflux or perhaps both?

We rarely do an ENT clinic without encountering a patient with persistent or recurring feeling of a lump or foreign body in the throat. We are also familiar with patients dreading to hear the C word after the endoscopic examination...

Finding the right balance: remote dizzy patient consultation during a pandemic

During the COVID pandemic, all our working patterns have changed. One significant impact had been on the management of outpatient consultations and the increase in telephone consultations and enhanced vetting. In this article the authors share their experience of managing...

A new tool to enhance smell recovery?

Vericiguat is a soluble guanylate cyclase activator which boosts intracellular cGMP and promotes smooth muscle relaxation. It is approved for use in heart failure, but the authors hypothesise that it may also enhance neuronal olfactory signalling via cGMP elevation. Eighty-eight...

Fibre-delivered transoral laser surgery – description of a novel technique

Transoral flexible laser surgery refers to the use of a fibre-delivered laser for laryngeal procedures via direct laryngoscopy. We hear of a novel innovation. The continuous development of instruments to perform endoscopic procedures for treatment of laryngotracheal pathology – among...

The first nine months: why early hearing matters more than ever

Why 1-3-6 and 9? They are arguably crucial intervention stages. Here, new science is explored which weaves together the threads of early intervention. Imagine a newborn gazing at their caregiver’s face, hearing their voice and feeling the rhythm of their...

Chin up, doc! A few simple manoeuvres could make all the difference in FNE

Flexible nasendoscopy (FNE) is an ENT surgeon’s bread and butter. It is integral and often considered superior to conventional radiography in the assessment of laryngeal and pharyngeal cancers. However, it is not as simple as sticking the camera in and...

Wearable tech revolutionising sleep monitoring: a new era in sleep health

Restful sleep is crucial for health but conditions like obstructive sleep apnoea (OSA) can significantly disrupt it, leading to fatigue, cardiovascular issues, and other serious health problems. Polysomnography (PSG) remains the gold standard for OSA diagnosis [1], however it is...

Well drilling vs. subperiosteal pocket for cochlear implants – comparison of operative time, complications and cost-effectiveness

The choice of method for securing the receiver/stimulator (R/S) package during cochlear implant surgery is usually dependant on several factors, but primarily surgeon preference. The initial recommendation from manufacturers was to drill a bony well (WD technique) and use bony...

Remote consultations: bringing ENT in to the 21st century

The ongoing peaks and troughs of the COVID-19 pandemic have imposed unprecedented challenges on day-to-day healthcare provision that we all took as given across the globe prior to spring 2020! The pandemic has, in many ways, made us push boundaries...

“It’s paediatric resus calling…”

This article is one of many within this issue that addresses a variety of ENT emergencies. The article outlined the stepwise process of assessing and managing a child with a suspected foreign body (FB) inhalation. Nuts, seeds and vegetable matter...

Call to action: dysphagia matters

Dysphagia profoundly impacts quality of life. Multidisciplinary research, like the POuCH study, aims to improve understanding, diagnosis and treatment. We take for granted the simple joys of life – meeting over a cup of coffee, breaking bread with friends or...