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Hearing loss and Alport syndrome
Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...In conversation with Professor Anne Schilder
Flying the flag for research in ENT, hearing and balance Anne Schilder is an NIHR Research Professor and leads the evidENT team at the Ear Institute at University College London. She also holds a Chair in Paediatric ENT at UCL...
Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer
The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...Electronic nicotine delivery systems (e-cigarettes): what you need to know
As an aid to stopping smoking e-cigarettes may have a role, but they are heavily promoted by industry as a leisure pursuit and desirable fashion accessory. Sneh Biyani and Craig Derkay gives a thorough account of what we know about...Clinical management: a personal view
When Nigel Beasley approached me to write on my experience of clinical management, I was a little surprised. I see myself as primarily a clinician, but have had increasing involvement with clinical management within my Trust. I am now in...Getting started in research
Dave had a passion for research and was very encouraging in developing a research interest in others. Bhavisha and Amanda are currently working with a team of researchers, patients, research funders, the Department of Health and Social Care and NHS England, to develop the 2023-2028 UK Action Plan for Hearing loss and Tinnitus Research - a set of recommendations to grow hearing research in the UK. Here, they discuss their journey to hearing care research and how you could get involved in the world of research.Preservation rhinoplasty
Hump reduction and osteotomies to close the open roof, or lowering the whole nasal dorsum? Charles East explains how preservation techniques can improve outcomes by maintaining the integral structures of the nose. What is preservation rhinoplasty? The origins of reduction...Long-term outcomes of children and young people with cochlear implants
Introduction Profound childhood hearing loss has a huge impact on early communication skills, the acquisition of spoken language, and hence on educational attainments and employment prospects. Over the centuries, educators of the deaf attempted to overcome the challenge by using...A global online fellowship in head and neck surgery and oncology
The International Federation of Head and Neck Oncologic Societies (IFHNOS) offers an online fellowship training programme for advanced trainees wishing to subspecialise in head and neck surgery and oncology. Emma Stapleton speaks with the Chairman of the Board of Directors...Laryngology: past, present and future
Two laryngological authorities trace the history of laryngology, from ancient Rome to the modern day. The structure of the vocal folds was a matter of conjecture until the renaissance when anatomists such as Andreas Vesalius and Julius Casserius demonstrated the...
Options for the endoscope and acquired cholesteatoma
This was a thought-provoking article examining the reasons why the authors believe that the endoscope is enabling an improved understanding of acquired cholesteatoma and its management. They describe in depth the ventilation pathways of the middle ear, and how they...
