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Gardasil vaccination as an adjuvant treatment for established recurrent laryngeal papillomatosis in male adults - does it stimulate an immune response?

Recurrent respiratory papillomatosis (RRP) is well known to be caused by infection with the human papilloma virus (types 6 and 11). Recurrence after surgical removal is common and potentially frequent and severe. Previous research has established that many patients with...

Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...

Sharing audio data for the greater good of research

HomeBank is a novel online repository for daylong audio recordings of children and families. Daylong recordings of children in naturalistic environments with their family and friends are an important source of information to enable an understanding of how children develop...

Sit back, relax and enjoy the flight! & Arrivals

This series of stories is dedicated to those of you with whom some of these moments were shared (or endured) and, above all, to my amazing and long-suffering husband, David Howard. Most of you know him as an exceptional head...

Olfaction in CRS

Conventional teaching tells us that hyposmia in chronic rhinosinusitis is due to mechanical obstruction of the olfactory cleft. But it might be that the story is slightly more complicated than that. Olfactory dysfunction is a common feature of chronic rhinosinusitis...

Parkinson’s humour: recognising social communication difficulties

Parkinson’s results in a progressive motor disease with symptoms including tremor, rigidity and bradykinesia. However, people with Parkinson’s also experience non-motor symptoms such as cognitive difficulties that can impact social communication, often due to their co-existing speech difficulties, auditory and...

Staphylococcus aureus as a cause of refractory chronic rhinosinusitis

Staphylococcus aureus has long been linked to chronic rhinosinusitis, particularly recalcitrant cases. In this article, Alkis Psaltis describes how newer techniques have shown higher rates of S. aureus infection than were previously thought, and explains how the bacteria are able...

Sleep apnoea in children with craniofacial syndromes

Whilst snoring and obstructive sleep apnoea are relatively common diagnoses in paediatric ENT, children with craniofacial syndromes take the problem to the next level. Robert Nash and Michelle Wyatt describe the Great Ormond Street multidisciplinary approach to treating this complex...

Can we prevent chronic rhinosinusitis?

The old adage ‘prevention is better than cure’ is considered by Professor Hopkins in respect to chronic rhinosinusitis, a condition affecting around 10% of the adult population and associated with huge impact on quality of life and economic cost. A...

Laryngotracheal stenosis

Airway stenosis has been an enormous challenge to laryngologists since the dawn of the sub-specialty. Careful evaluation is essential, as this will determine the best treatment. We hear more from one of the UK’s leading airway centres. Until the advent...

Developing medical devices for children: opportunities and challenges

The development of medical devices for infants and children lags significantly behind the development of devices for adults. While in the United States the Food and Drug Administration (FDA) has set up incentives for developing child age-specific pharmaceuticals, there is...

ESPO 2020

Professor Wytske Fokkens and Professor Valerie Lund on behalf of the EPOS2020 steering group [1] EPOS2020 steering group at final meeting in Leiden, November 2019. In February this year, EPOS2020 was published as a supplement in Rhinology [1], the latest...