You searched for "molecular"

304 results found

Detecting postoperative cholesteatoma with diffusion weighted magnetic resonance imaging

Middle ear cleft cholesteatoma is an inflammatory disease that erodes local bony structures and can cause otorrhea, hearing loss, vertigo and intracranial complications. It is usually treated with surgery, typically canal wall up (CWU) or canal wall down (CWD) surgery....

The Brain’s Connectome – a symphony inside our brains and how hearing loss disturbs the music

Understand us; where do we begin? In this article the authors’ introduce a project that may uncover that our personalities and traits are a product of the interconnected wiring within our brain. The team discusses the Human Connectome Project and...

Is bone cement a cost-effective solution?

This study looks at the functional results of 52 patients who underwent bone cement ossiculoplasty. Patients were divided into four groups based on ossicular disruption. Group 1 (30 patients) had lenticular erosion only. Group 2 (13 patients) had absent incus....

Branchio Oto Renal syndrome

Branchio Oto Renal Syndrome (BOR) is an autosomal dominant disorder with branchial, otologic and renal manifestations. The presence of clinical signs varies among and within affected families. Three causative genes for BOR syndrome have been reported thus far: EYA1, SIX1...

Dysphagia in complex laryngology – maintaining the balance

These authors from the speech and language therapy department at Imperial College Healthcare NHS Trust, describe their view of a patient-centred approach to managing dysphagia in complex laryngology. Careful consideration of the balance of airway, voice and swallow, which is...

What works better for type 3 tympanoplasty?

This is a systematic review comparing incus transposition (IT) and partial ossicular replacement prosthesis (PORP). There is a total of 14 articles, obtaining 1055 patients: 614 for the IT group and 441 for the PORP group. All included patients had...

Rhinology: what does the future hold?

David Kennedy surveys the past, the present and the future of rhinology practice and research. An evolution of understanding in rhinology The dramatic growth of clinical and translational research within the field of rhinology in recent years is illustrated by...

Prospective evaluation of quality of life in the flaccid

Flaccid midface paralysis causes nasal valve collapse due to the lack of tonic muscular support. This causes both external nasal valve narrowing and collapse during inspiration. Correction of the nasal valve is performed in functional rhinoplasty. However, these procedures do...

All about velopharyngeal dysfunction

The velopharynx functionally separates the oral from the nasal cavities. Inadequate or abnormal function of this muscular valve affects speech and swallow. Velopharyngeal dysfunction can be subdivided into insufficiency, incompetence and mislearning. This is a review paper and indeed a...

Association of diabetes mellitus type 2 with age-related changes in the larynx

Diabetes affects the body with changes in the neurological, muscular and vascular systems. It is therefore conceivable that the larynx, which is a musculoskeletal organ, can be adversely affected by type 2 diabetes mellitus. To explore this possibility, 174 Caucasian...

Does pregabalin help with post-tonsillectomy pain?

This is a small double-blind randomised controlled trial conducted on tonsillectomy and lateral pharyngoplasty operations. Both of these operations are terrifically painful, and I am sure most of us are looking for a way of reducing the suffering for our...

Paediatric vestibular evaluation

Richard E Gans is a renowned expert in the areas of vestibular evaluation and rehabilitation techniques. In the first of two articles (see here for the second article), Dr Gans gives an overview of the approach he and his team...