You searched for "molecular"

302 results found

The future of rhinology: What will come first, a radical change in rhinological management or the decimation of the world?

In this article, Simon Gane looks forward to what the future holds, on the presumption he survives. Setting aside the questions of the UK even existing, the NHS still working, or the fact we’ll be commuting to our jobs in...

Laryngology: past, present and future

Two laryngological authorities trace the history of laryngology, from ancient Rome to the modern day. The structure of the vocal folds was a matter of conjecture until the renaissance when anatomists such as Andreas Vesalius and Julius Casserius demonstrated the...

What’s happened since the European position paper on nose and sinus tumours?

The management of malignant sinonasal tumours has gone through radical changes in recent years. Prof Valerie Lund gives us an update based on her upcoming talk at IFOS. In 2010 when we published the European position paper on ‘endoscopic management...

Branchio Oto Renal syndrome

Branchio Oto Renal Syndrome (BOR) is an autosomal dominant disorder with branchial, otologic and renal manifestations. The presence of clinical signs varies among and within affected families. Three causative genes for BOR syndrome have been reported thus far: EYA1, SIX1...

Dysphagia in complex laryngology – maintaining the balance

These authors from the speech and language therapy department at Imperial College Healthcare NHS Trust, describe their view of a patient-centred approach to managing dysphagia in complex laryngology. Careful consideration of the balance of airway, voice and swallow, which is...

What works better for type 3 tympanoplasty?

This is a systematic review comparing incus transposition (IT) and partial ossicular replacement prosthesis (PORP). There is a total of 14 articles, obtaining 1055 patients: 614 for the IT group and 441 for the PORP group. All included patients had...

Paediatric vestibular evaluation

Richard E Gans is a renowned expert in the areas of vestibular evaluation and rehabilitation techniques. In the first of two articles (see here for the second article), Dr Gans gives an overview of the approach he and his team...

Rhinology: what does the future hold?

David Kennedy surveys the past, the present and the future of rhinology practice and research. An evolution of understanding in rhinology The dramatic growth of clinical and translational research within the field of rhinology in recent years is illustrated by...

Prospective evaluation of quality of life in the flaccid

Flaccid midface paralysis causes nasal valve collapse due to the lack of tonic muscular support. This causes both external nasal valve narrowing and collapse during inspiration. Correction of the nasal valve is performed in functional rhinoplasty. However, these procedures do...

All about velopharyngeal dysfunction

The velopharynx functionally separates the oral from the nasal cavities. Inadequate or abnormal function of this muscular valve affects speech and swallow. Velopharyngeal dysfunction can be subdivided into insufficiency, incompetence and mislearning. This is a review paper and indeed a...

Association of diabetes mellitus type 2 with age-related changes in the larynx

Diabetes affects the body with changes in the neurological, muscular and vascular systems. It is therefore conceivable that the larynx, which is a musculoskeletal organ, can be adversely affected by type 2 diabetes mellitus. To explore this possibility, 174 Caucasian...

Does pregabalin help with post-tonsillectomy pain?

This is a small double-blind randomised controlled trial conducted on tonsillectomy and lateral pharyngoplasty operations. Both of these operations are terrifically painful, and I am sure most of us are looking for a way of reducing the suffering for our...