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Is there increased cardiovascular risk with macrolide antibiotics?
This month’s Ed’s Choice delightfully reviews the potential cardiovascular consequences of long-term macrolide use in the treatment of chronic rhinosinusitis. This used to be one of my ‘go-to’ topics of conversation at home after a bad day at work, although...The Dilemma of Beethoven’s Deafness
Beethoven was one of the world’s greatest musicians, and his deafness is well known. Many details of his medical conditions are known, and various theories of his hearing loss have been proposed. Ludwig van Beethoven was born in 1770 in...Intratympanic treatments for subjective idiopathic tinnitus
Direct application of medication into the ear is long established, going back as far as written records. In the modern era, greater understanding of aural anatomy revealed that drugs instilled in the middle ear could potentially diffuse into the cochlea...The impact of vocal care and oral health on laryngeal function and voice
Maintenance of epithelial health relies on a number of measures. We hear about hydration, irritants and biofilms from a team in Helsinki. Oropharyngeal health Vocal hygiene is a commonly used term that refers to the personal daily habits contributing to...The role of macrolide antibiotics in chronic rhinosinusitis
The use of long-term antibiotics in the treatment of chronic rhinosinusitis is a contentious issue, not only because of the increasing problem with antibiotic resistance but also because of the potential cardiac risks, including sudden death. In this article, Anders...Recalcitrant chronic rhinosinusitis: What to do next?
Whilst the majority of patients with chronic rhinosinusitis (CRS) will significantly improve with treatment, we are sometimes left with a ‘hard-core’ of nasal cripples who fail to improve despite our best efforts. How can we deal with these patients? Valerie...The future of inner ear drug delivery
The techniques for delivering drugs to the inner ear system are evolving. Jeffrey Harris considers the myths, the facts and the potential for drug delivery innovations and how they can improve tomorrow’s hearing outcomes. The inner ear’s delicate membranous structure,...
Eosinophilic or not eosinophilic: dupilumab seems to work
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammation with interleukin (IL)-4, IL-13, and IL-5. Tissue eosinophilia in nasal polyps dramatically increased over a 10-20-year period. Classification of the severity of eosinophil status is expected to lead to...
Medication and its effect on the larynx
This article summarises different medications and their effect on the voice. A growing number of patients we see in clinic are on multiple medications that could affect vocal cord function. The author summarises different classes of medications and their potential...
Platelet-rich plasma to reduce post-tonsillectomy haemorrhage and pain
Minimising haemorrhage and promoting healing of raw areas are cornerstones for uneventful and speedy recovery after tonsillectomy. In this single-blinded prospective experimental study, application of platelet-rich plasma to one side tonsillar bed has been compared to the other side in...
Nasal disease and quality of life in athletes
Rhinitis is a nasal condition which is generally underappreciated in primary care and even less in athletes. In this study, the authors specify nasal symptoms constituting rhinitis as nasal blockage, sneezing bouts, rhinorrhoea and itching and compare their prevalence in...
