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The future of inner ear drug delivery
The techniques for delivering drugs to the inner ear system are evolving. Jeffrey Harris considers the myths, the facts and the potential for drug delivery innovations and how they can improve tomorrow’s hearing outcomes. The inner ear’s delicate membranous structure,...
Inner ear immunity
There is much speculation regarding the ear’s immune response. The environment in which we live and breathe is getting ever more complex; aspects such as the percentage of the population with autoimmune conditions are on the rise and, therefore, it...In this issue...Inner Ear Therapeutics
Emma Stapleton, MBChB, FRCS (ORL-HNS), Consultant Otolaryngologist, Cochlear Implant and Skull Base Surgeon, Manchester Royal Infirmary, UK. E: emmastapleton@doctors.org.ukTwitter: @otolaryngolofox Ralph Holme, Director of Research and Insight, RNID, UK. Ralph. E: Holme@rnid.org.uk W: www.rnid.org.uk For Mar/Apr 2022, we sang the...
Cochlear implantation and inner ear malformations
In this study the authors attempted to compare the outcomes in children who underwent cochlear implantation (CI) with inner ear malformations to those that had normal inner ear anatomy. Sixty three children with prelingual deafness who underwent CI were included....
Vestibular schwannoma surgery and inner ear injuries
Iatrogenic inner ear injury during vestibular schwannoma (VS) surgery ranges between 20% and 30% in the literature. However, there is no up-to-date quantification of such injuries, hence this study. The authors conducted a US-multicentre database search looking for patients who...Microneedles enable inner ear precision medicine
Developing safe, reliable and efficient ways to deliver therapeutics into the cochlea is a key challenge. In this article, the authors share their work to develop microneedles to address this challenge. The era of precision medicine of the inner ear...
Cochlear implantation in inner ear schwannoma patients
Inner ear schwannomas (IES) are rare. Patients with IES tend to lose their hearing. Surgery is a treatment option, but it leads to complete loss of hearing. Other treatment options include stereotactic radiosurgery (SRS) and watchful waiting (WW). The authors...
What we need to know about the new frontier of inner ear therapies
This is an interesting and topical review of the emerging biotechnology and pharmaceutical solutions for hearing loss and related conditions such as tinnitus. This paper suggests we are on the cusp of a very large step-change in the way we...Illuminating ear education: building interactive models to enhance inner ear understanding
Understanding the anatomy and function of the inner ear, particularly the vestibular apparatus and cochlea, is fundamental to audiology and otolaryngology education. However, the complex geometry and intricate functional relationships of these structures challenge us to find clear ways to...
