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Neuromodulation in drug resistant epilepsy
Treatment of epilepsy can be considered generally as medical or surgical. Anti-epileptic drugs achieve a five-year seizure freedom in 54-70% patients. It is estimated that 50-90% of patients with drug-refractory epilepsy may not be candidates for resective surgery. For example,...
Drug-Induced Sleep Endoscopy
Throughout our ENT careers, we will always be referred patients with sleep-disordered breathing - both adults and children. Sleep studies are key for this condition. I remember as a trainee in the early aspect of my career seeing the sleep...The future of inner ear drug delivery
The techniques for delivering drugs to the inner ear system are evolving. Jeffrey Harris considers the myths, the facts and the potential for drug delivery innovations and how they can improve tomorrow’s hearing outcomes. The inner ear’s delicate membranous structure,...Adolescence, drug use and body image
Teenagers are notoriously conscious of how they are perceived by others. Dr Saraiva and colleagues explain how this can lead to problems with substance abuse for both boys and girls, and discuss the different substances they may encounter. Adolescence is...
A drug to prevent hearing loss caused by ototoxic therapeutics
This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...Drug side-effects on audiological and vestibular testing
Are they a malingerer? Or perhaps they are inattentive? It may be their drugs! Robert DiSogra considers the side-effects of medication on the test subject. The audiogram serves many purposes in clinical practice. For the audiologist, it helps to differentiate...
Drug eluting stent vs INCS for CRS
A prospective, randomised study from Finland to compare a drug eluting stent (DES) and intranasal corticosteroids (INCS) in 63 patients as assessed by SNOT-22, VAS, endoscopy, CT and rhinometry pre-treatment, at three and six months post treatment. Recruitment was over...
