A randomised controlled study of 37 patients took place that underwent endoscopic sinus surgery for chronic rhinosinusitis and received adrenaline or cocaine-soaked patties. The study showed no difference in the mean surgical field scores between adrenaline and cocaine sides. Adequate surgical field visualisation is among the most important factors in preventing complications in functional endoscopic sinus surgery, but this study was small and limited. 

Topical cocaine vs adrenaline in endoscopic sinus surgery: a blinded randomized controlled study.
Valdes CJ, Bogado M, Rammal A, et al.
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY
2014;4(8):646-50.
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Laith Tapponi

Wiltshire, UK.

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