There are a multitude of ways in which to damage the nasal epithelium, whether iatrogenically through nasal surgery, via injury, allergy, infection or inhalation of an environmental pollutant. This study looks at the role of the herb rosemary, in the form of rosmarinic acid, in the healing of the nasal mucosa of rats. The main bioactive compounds are polyphenols such as rosmarinic acid and carnosic acid, and the authors hypothesise that these can have a role in promoting the healing of damaged nasal mucosa. The nasal mucosa of 21 anaesthetised rats were damaged using a brush, and the rats were subsequently divided into three groups: one control group, one treated topically with rosmarinic acid and one group treated with systemic rosmarinic acid. The results showed that both the local and systemic treatment groups had significantly improved wound healing when compared to the control across all the histopathological parameters assessed, the systemic application being the most beneficial. This is very interesting and potentially hugely beneficial in the future for improving recovery rates and healing following nasal surgeries like FESS and septoplasty, although extensive further surgery is required before this assumption is made, as the mechanism of effect is unknown.
Rosemary oil to aid surgical healing?
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