This group conducted a one year prospective study and sampled mucosa from 42 randomly selected patients with septal deviation at a single centre. They found significantly higher rate of squamous metaplasia and lymphocytic infiltration in septal mucosa on the concave side versus convex side. They conclude that a deviated nasal septum predisposes the nasal epithelium to chronic inflammation and squamous metaplasia (due to air flow). Whether or not this predisposes the patient to increased rates of chronic rhinosinusitis or cancer remains to be seen.