Journal Reviews

Auris Nasus Larynx journal cover image.

Pharmacological treatment of glue ear in children

5 July 2022 | | Audiology - Paediatric, Otology | Antihistamines, leukotriene receptor antagonist, Carbocysteine, Meta-analysis, Otitis media with effusion, Steroid nasal spray, Systematic review

Otitis media with effusion (OME), also known as glue ear, is a common cause of hearing loss in children. Most cases resolve spontaneously within three months. Early and proper management of OME can help avoid hearing and speech impairment that...

Prostaglandin versus leukotriene receptor-antagonists in treatment of seasonal allergic rhinitis RCT phase II

1 January 2018 | | Bayesian posterior probability, allergic rhinitis, leukotriene receptor antagonist, mast cell degranulation, prostaglandin D2 receptor 1 antagonist

Seasonal allergic rhinitis is very common. Failure to control the disease with mono-therapy leads to dual therapy treatment with less compliance and reduced quality of life. A prostaglandin receptor antagonist (ONO-4053) showed some efficacy in controlling allergic rhinitis in animal...